Sitagliptin Reduces Endothelial Dysfunction and Apoptosis Induced by High-Fat Diet and Palmitate in Thoracic Aortas and Endothelial Cells via ROS-ER Stress-CHOP Pathway.

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Title: Sitagliptin Reduces Endothelial Dysfunction and Apoptosis Induced by High-Fat Diet and Palmitate in Thoracic Aortas and Endothelial Cells via ROS-ER Stress-CHOP Pathway.
Authors: Cao Q; Department of Biochemistry and Molecular Biology, Hefei, China., Xu D; Department of Biochemistry and Molecular Biology, Hefei, China., Chen Y; Hefei Lifeon Pharmaceutical Co. Ltd., Hefei, China., Long Y; Department of Biochemistry and Molecular Biology, Hefei, China., Dai F; Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, China., Gui L; The Comprehensive Laboratory, School of Basic Medical Science, Anhui Medical University, Hefei, China., Lu Y; Department of Biochemistry and Molecular Biology, Hefei, China.; The Comprehensive Laboratory, School of Basic Medical Science, Anhui Medical University, Hefei, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2021 Aug 31; Vol. 12, pp. 670389. Date of Electronic Publication: 2021 Aug 31 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2021.670389