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Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin.

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Title: Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin.
Authors: Lee KJ; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Chang WL; Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Chen X; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Valiyaveettil J; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Ramirez-Alcantara V; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Gavin E; Gynecologic Oncology Research Division, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Musiyenko A; Gynecologic Oncology Research Division, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Madeira da Silva L; Gynecologic Oncology Research Division, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Annamdevula NS; Department of Chemical and Biomedical Engineering, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama., Leavesley SJ; Department of Chemical and Biomedical Engineering, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.; Department of Pharmacology, University of South Alabama, Mobile, Alabama., Ward A; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Mattox T; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Lindsey AS; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Andrews J; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Zhu B; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Wood C; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Neese A; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Nguyen A; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Berry K; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Maxuitenko Y; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, Alabama., Moyer MP; INCELL Corporation LLC, San Antonio, Texas., Nurmemmedov E; Saint John's Cancer Institute, Santa Monica, California., Gorman G; Samford University, Birmingham, Alabama., Coward L; Samford University, Birmingham, Alabama., Zhou G; Georgia Cancer Center, Augusta University, Augusta, Georgia., Keeton AB; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, Alabama., Cooper HS; Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Clapper ML; Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Piazza GA; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, Alabama. gap0034@auburn.edu.
Source: Cancer prevention research (Philadelphia, Pa.) [Cancer Prev Res (Phila)] 2021 Nov; Vol. 14 (11), pp. 995-1008. Date of Electronic Publication: 2021 Sep 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101479409 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1940-6215 (Electronic) Linking ISSN: 19406215 NLM ISO Abbreviation: Cancer Prev Res (Phila) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin.
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  Data: <searchLink fieldCode="AU" term="%22Lee+KJ%22">Lee KJ</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Chang+WL%22">Chang WL</searchLink>; Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Valiyaveettil+J%22">Valiyaveettil J</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Ramirez-Alcantara+V%22">Ramirez-Alcantara V</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Gavin+E%22">Gavin E</searchLink>; Gynecologic Oncology Research Division, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Musiyenko+A%22">Musiyenko A</searchLink>; Gynecologic Oncology Research Division, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Madeira+da+Silva+L%22">Madeira da Silva L</searchLink>; Gynecologic Oncology Research Division, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Annamdevula+NS%22">Annamdevula NS</searchLink>; Department of Chemical and Biomedical Engineering, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Leavesley+SJ%22">Leavesley SJ</searchLink>; Department of Chemical and Biomedical Engineering, University of South Alabama, Mobile, Alabama.; Center for Lung Biology, University of South Alabama, Mobile, Alabama.; Department of Pharmacology, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Ward+A%22">Ward A</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Mattox+T%22">Mattox T</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Lindsey+AS%22">Lindsey AS</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Andrews+J%22">Andrews J</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Zhu+B%22">Zhu B</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Wood+C%22">Wood C</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Neese+A%22">Neese A</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Nguyen+A%22">Nguyen A</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Berry+K%22">Berry K</searchLink>; Drug Discovery Research Center, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama.<br /><searchLink fieldCode="AU" term="%22Maxuitenko+Y%22">Maxuitenko Y</searchLink>; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, Alabama.<br /><searchLink fieldCode="AU" term="%22Moyer+MP%22">Moyer MP</searchLink>; INCELL Corporation LLC, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Nurmemmedov+E%22">Nurmemmedov E</searchLink>; Saint John's Cancer Institute, Santa Monica, California.<br /><searchLink fieldCode="AU" term="%22Gorman+G%22">Gorman G</searchLink>; Samford University, Birmingham, Alabama.<br /><searchLink fieldCode="AU" term="%22Coward+L%22">Coward L</searchLink>; Samford University, Birmingham, Alabama.<br /><searchLink fieldCode="AU" term="%22Zhou+G%22">Zhou G</searchLink>; Georgia Cancer Center, Augusta University, Augusta, Georgia.<br /><searchLink fieldCode="AU" term="%22Keeton+AB%22">Keeton AB</searchLink>; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, Alabama.<br /><searchLink fieldCode="AU" term="%22Cooper+HS%22">Cooper HS</searchLink>; Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Clapper+ML%22">Clapper ML</searchLink>; Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Piazza+GA%22">Piazza GA</searchLink>; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, Alabama. gap0034@auburn.edu.
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  Data: <searchLink fieldCode="JN" term="%22101479409%22">Cancer prevention research (Philadelphia, Pa.)</searchLink> [Cancer Prev Res (Phila)] 2021 Nov; Vol. 14 (11), pp. 995-1008. <i>Date of Electronic Publication: </i>2021 Sep 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101479409 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1940-6215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219406215%22">19406215 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Prev Res (Phila) <i>Subsets: </i>MEDLINE
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