CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background.

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Title: CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background.
Authors: Lum JS; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Brown ML; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Farrawell NE; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., McAlary L; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Ly D; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Chisholm CG; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Snow J; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Vine KL; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Karl T; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia., Kreilaus F; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia., McInnes LE; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia., Nikseresht S; Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia., Donnelly PS; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia., Crouch PJ; Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia., Yerbury JJ; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia. jyerbury@uow.edu.au.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia. jyerbury@uow.edu.au.
Source: Scientific reports [Sci Rep] 2021 Sep 29; Vol. 11 (1), pp. 19392. Date of Electronic Publication: 2021 Sep 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-021-98317-w