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CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background.

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Title: CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background.
Authors: Lum JS; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Brown ML; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Farrawell NE; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., McAlary L; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Ly D; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Chisholm CG; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Snow J; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Vine KL; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia., Karl T; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia., Kreilaus F; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia., McInnes LE; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia., Nikseresht S; Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia., Donnelly PS; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia., Crouch PJ; Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia., Yerbury JJ; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia. jyerbury@uow.edu.au.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia. jyerbury@uow.edu.au.
Source: Scientific reports [Sci Rep] 2021 Sep 29; Vol. 11 (1), pp. 19392. Date of Electronic Publication: 2021 Sep 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1<superscript>G93A</superscript> mice with a C57BL/6 background.
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  Data: <searchLink fieldCode="AU" term="%22Lum+JS%22">Lum JS</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+ML%22">Brown ML</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Farrawell+NE%22">Farrawell NE</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22McAlary+L%22">McAlary L</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Ly+D%22">Ly D</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Chisholm+CG%22">Chisholm CG</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Snow+J%22">Snow J</searchLink>; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Vine+KL%22">Vine KL</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.<br /><searchLink fieldCode="AU" term="%22Karl+T%22">Karl T</searchLink>; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia.<br /><searchLink fieldCode="AU" term="%22Kreilaus+F%22">Kreilaus F</searchLink>; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia.<br /><searchLink fieldCode="AU" term="%22McInnes+LE%22">McInnes LE</searchLink>; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Nikseresht+S%22">Nikseresht S</searchLink>; Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Donnelly+PS%22">Donnelly PS</searchLink>; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Crouch+PJ%22">Crouch PJ</searchLink>; Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Yerbury+JJ%22">Yerbury JJ</searchLink>; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia. jyerbury@uow.edu.au.; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia. jyerbury@uow.edu.au.
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