Interactions in clinical trials: Protocol and statistical analysis plan for an explorative study of four randomized ICU trials on use of pantoprazole, oxygenation targets, haloperidol and intravenous fluids.

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Title: Interactions in clinical trials: Protocol and statistical analysis plan for an explorative study of four randomized ICU trials on use of pantoprazole, oxygenation targets, haloperidol and intravenous fluids.
Authors: Schjørring OL; Department of Anaesthesia and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark., Lange T; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Public Health, Section of Biostatistics, Copenhagen University, Copenhagen, Denmark., Krag M; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Intensive Care, Rigshospitalet, Copenhagen, Denmark.; Department of Anaesthesiology and Intensive Care, Holbaek Hospital, Holbaek, Denmark., Andersen-Ranberg NC; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Anaesthesiology, Zealand University Hospital, Køge, Denmark., Meyhoff TS; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Intensive Care, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Marker S; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Intensive Care, Rigshospitalet, Copenhagen, Denmark., Klitgaard TL; Department of Anaesthesia and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark., Estrup S; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Anaesthesiology, Zealand University Hospital, Køge, Denmark., Møller MH; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Intensive Care, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Rasmussen BS; Department of Anaesthesia and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark., Poulsen LM; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Anaesthesiology, Zealand University Hospital, Køge, Denmark., Perner A; Centre for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Intensive Care, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Source: Acta anaesthesiologica Scandinavica [Acta Anaesthesiol Scand] 2022 Jan; Vol. 66 (1), pp. 156-162. Date of Electronic Publication: 2021 Oct 10.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0370270 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-6576 (Electronic) Linking ISSN: 00015172 NLM ISO Abbreviation: Acta Anaesthesiol Scand Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1399-6576
DOI:10.1111/aas.13990