Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models.
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| Title: | Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models. |
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| Authors: | Kopczynski M; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland., Rumienczyk I; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland., Kulecka M; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland.; Department of Gastroenterology, Hepatology and Clinical Oncology, Centre for Postgraduate Medical Education, 01-813 Warsaw, Poland., Statkiewicz M; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland., Pysniak K; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland., Sandowska-Markiewicz Z; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland., Wojcik-Trechcinska U; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland., Goryca K; Genomics Core Facility, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland., Pyziak K; Biology R&D, Ryvu Therapeutics S.A., 30-394 Krakow, Poland., Majewska E; Biology R&D, Ryvu Therapeutics S.A., 30-394 Krakow, Poland., Masiejczyk M; Biology R&D, Ryvu Therapeutics S.A., 30-394 Krakow, Poland., Wojcik-Jaszczynska K; Biology R&D, Ryvu Therapeutics S.A., 30-394 Krakow, Poland., Rzymski T; Biology R&D, Ryvu Therapeutics S.A., 30-394 Krakow, Poland., Bomsztyk K; UW Medicine South Lake Union, University of Washington, Seattle, WA 98109, USA., Ostrowski J; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland.; Department of Gastroenterology, Hepatology and Clinical Oncology, Centre for Postgraduate Medical Education, 01-813 Warsaw, Poland., Mikula M; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland. |
| Source: | International journal of molecular sciences [Int J Mol Sci] 2021 Sep 22; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1422-0067 |
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| DOI: | 10.3390/ijms221910204 |