First-Line Nivolumab Plus Ipilimumab in Advanced NSCLC: 4-Year Outcomes From the Randomized, Open-Label, Phase 3 CheckMate 227 Part 1 Trial.

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Title: First-Line Nivolumab Plus Ipilimumab in Advanced NSCLC: 4-Year Outcomes From the Randomized, Open-Label, Phase 3 CheckMate 227 Part 1 Trial.
Authors: Paz-Ares LG; Hospital Universitario 12 de Octubre, H12O-CNIO Lung Cancer Clinical Research Unit, Universidad Complutense & CiberOnc, Madrid, Spain. Electronic address: lpazaresr@seom.org., Ramalingam SS; Winship Cancer Institute, Emory University, Atlanta, Georgia., Ciuleanu TE; Institutul Oncologic Prof Dr Ion Chiricuta and UMF Iuliu Hatieganu, Cluj Napoca, România., Lee JS; Seoul National University Bundang Hospital, Seongnam, Republic of Korea., Urban L; Matrai Gyogyintezet, Matrahaza, Hungary., Caro RB; Hospital Universitario Virgen Del Rocio, Instituto de Biomedicina de Seville, Seville, Spain., Park K; Samsung Medical Center at Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Sakai H; Saitama Cancer Center, Saitama, Japan., Ohe Y; National Cancer Center Hospital, Tokyo, Japan., Nishio M; Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan., Audigier-Valette C; Hôpital Sainte Musse, Toulon, France., Burgers JA; Netherlands Cancer Institute, Amsterdam, The Netherlands., Pluzanski A; Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Sangha R; Cross Cancer Institute, Edmonton, Alberta, Canada., Gallardo C; Fundacion Arturo Lopez Perez, Santiago, Chile., Takeda M; Kindai University Faculty of Medicine, Osaka, Japan., Linardou H; Metropolitan Hospital, Neo Faliro, Greece., Lupinacci L; Hospital Italiano De Buenos Aires, Buenos Aires, Argentina., Lee KH; Chungbuk National University Hospital, Cheongju-si, Republic of Korea., Caserta C; Santa Maria Hospital, Terni, Italy., Provencio M; Hosp. Univ. Puerta De Hierro-IDIPHIM, Universidad Autónoma de Madrid, Madrid, Spain., Carcereny E; Catalan Institute of Oncology-Germans Trias i Pujol Hospital, B-ARGO group, Badalona, Spain., Otterson GA; The Ohio State University, Columbus, Ohio., Schenker M; SF. Nectarie Oncology Center, Craiova, Romania., Zurawski B; Ambulatorium Chemioterapii, Bydgoszcz, Poland., Alexandru A; Institute of Oncology 'Prof. Dr. Alexandru Trestioreanu' Bucha, Bucharest, Romania., Vergnenegre A; Limoges University Hospital, Limoges, France., Raimbourg J; ICO Rene Gauducheau, St Herblain, France., Feeney K; St John of God Hospital Murdoch, Perth, Australia., Kim SW; Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Borghaei H; Fox Chase Cancer Center, Philadelphia, Pennsylvania., O'Byrne KJ; Queensland University of Technology, Princess Alexandra Hospital, Brisbane, Australia., Hellmann MD; Memorial Sloan Kettering Cancer Center, New York, New York., Memaj A; Bristol Myers Squibb, Princeton, New Jersey., Nathan FE; Bristol Myers Squibb, Princeton, New Jersey., Bushong J; Bristol Myers Squibb, Princeton, New Jersey., Tran P; Bristol Myers Squibb, Princeton, New Jersey., Brahmer JR; Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland., Reck M; Airway Research Center North, German Center for Lung Research, LungClinic, Grosshansdorf, Germany.
Source: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2022 Feb; Vol. 17 (2), pp. 289-308. Date of Electronic Publication: 2021 Oct 12.
Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101274235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-1380 (Electronic) Linking ISSN: 15560864 NLM ISO Abbreviation: J Thorac Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: First-Line Nivolumab Plus Ipilimumab in Advanced NSCLC: 4-Year Outcomes From the Randomized, Open-Label, Phase 3 CheckMate 227 Part 1 Trial.
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  Data: <searchLink fieldCode="AU" term="%22Paz-Ares+LG%22">Paz-Ares LG</searchLink>; Hospital Universitario 12 de Octubre, H12O-CNIO Lung Cancer Clinical Research Unit, Universidad Complutense & CiberOnc, Madrid, Spain. Electronic address: lpazaresr@seom.org.<br /><searchLink fieldCode="AU" term="%22Ramalingam+SS%22">Ramalingam SS</searchLink>; Winship Cancer Institute, Emory University, Atlanta, Georgia.<br /><searchLink fieldCode="AU" term="%22Ciuleanu+TE%22">Ciuleanu TE</searchLink>; Institutul Oncologic Prof Dr Ion Chiricuta and UMF Iuliu Hatieganu, Cluj Napoca, România.<br /><searchLink fieldCode="AU" term="%22Lee+JS%22">Lee JS</searchLink>; Seoul National University Bundang Hospital, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Urban+L%22">Urban L</searchLink>; Matrai Gyogyintezet, Matrahaza, Hungary.<br /><searchLink fieldCode="AU" term="%22Caro+RB%22">Caro RB</searchLink>; Hospital Universitario Virgen Del Rocio, Instituto de Biomedicina de Seville, Seville, Spain.<br /><searchLink fieldCode="AU" term="%22Park+K%22">Park K</searchLink>; Samsung Medical Center at Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sakai+H%22">Sakai H</searchLink>; Saitama Cancer Center, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Ohe+Y%22">Ohe Y</searchLink>; National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nishio+M%22">Nishio M</searchLink>; Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Audigier-Valette+C%22">Audigier-Valette C</searchLink>; Hôpital Sainte Musse, Toulon, France.<br /><searchLink fieldCode="AU" term="%22Burgers+JA%22">Burgers JA</searchLink>; Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pluzanski+A%22">Pluzanski A</searchLink>; Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Sangha+R%22">Sangha R</searchLink>; Cross Cancer Institute, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Gallardo+C%22">Gallardo C</searchLink>; Fundacion Arturo Lopez Perez, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Takeda+M%22">Takeda M</searchLink>; Kindai University Faculty of Medicine, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Linardou+H%22">Linardou H</searchLink>; Metropolitan Hospital, Neo Faliro, Greece.<br /><searchLink fieldCode="AU" term="%22Lupinacci+L%22">Lupinacci L</searchLink>; Hospital Italiano De Buenos Aires, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Lee+KH%22">Lee KH</searchLink>; Chungbuk National University Hospital, Cheongju-si, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Caserta+C%22">Caserta C</searchLink>; Santa Maria Hospital, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Provencio+M%22">Provencio M</searchLink>; Hosp. Univ. Puerta De Hierro-IDIPHIM, Universidad Autónoma de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Carcereny+E%22">Carcereny E</searchLink>; Catalan Institute of Oncology-Germans Trias i Pujol Hospital, B-ARGO group, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Otterson+GA%22">Otterson GA</searchLink>; The Ohio State University, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Schenker+M%22">Schenker M</searchLink>; SF. Nectarie Oncology Center, Craiova, Romania.<br /><searchLink fieldCode="AU" term="%22Zurawski+B%22">Zurawski B</searchLink>; Ambulatorium Chemioterapii, Bydgoszcz, Poland.<br /><searchLink fieldCode="AU" term="%22Alexandru+A%22">Alexandru A</searchLink>; Institute of Oncology 'Prof. Dr. Alexandru Trestioreanu' Bucha, Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Vergnenegre+A%22">Vergnenegre A</searchLink>; Limoges University Hospital, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Raimbourg+J%22">Raimbourg J</searchLink>; ICO Rene Gauducheau, St Herblain, France.<br /><searchLink fieldCode="AU" term="%22Feeney+K%22">Feeney K</searchLink>; St John of God Hospital Murdoch, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Kim+SW%22">Kim SW</searchLink>; Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Borghaei+H%22">Borghaei H</searchLink>; Fox Chase Cancer Center, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22O'Byrne+KJ%22">O'Byrne KJ</searchLink>; Queensland University of Technology, Princess Alexandra Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Hellmann+MD%22">Hellmann MD</searchLink>; Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Memaj+A%22">Memaj A</searchLink>; Bristol Myers Squibb, Princeton, New Jersey.<br /><searchLink fieldCode="AU" term="%22Nathan+FE%22">Nathan FE</searchLink>; Bristol Myers Squibb, Princeton, New Jersey.<br /><searchLink fieldCode="AU" term="%22Bushong+J%22">Bushong J</searchLink>; Bristol Myers Squibb, Princeton, New Jersey.<br /><searchLink fieldCode="AU" term="%22Tran+P%22">Tran P</searchLink>; Bristol Myers Squibb, Princeton, New Jersey.<br /><searchLink fieldCode="AU" term="%22Brahmer+JR%22">Brahmer JR</searchLink>; Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Reck+M%22">Reck M</searchLink>; Airway Research Center North, German Center for Lung Research, LungClinic, Grosshansdorf, Germany.
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