Modeling restoration of gefitinib efficacy by co-administration of MET inhibitors in an EGFR inhibitor-resistant NSCLC xenograft model: A tumor-in-host DEB-based approach.
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| Title: | Modeling restoration of gefitinib efficacy by co-administration of MET inhibitors in an EGFR inhibitor-resistant NSCLC xenograft model: A tumor-in-host DEB-based approach. |
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| Authors: | Tosca EM; Laboratory of Bioinformatics, Mathematical Modelling and Synthetic Biology, Department of Electrical, Computer and Biomedical Engineering, Università degli Studi di Pavia, Pavia, Italy., Gauderat G; Clinical Pharmacokinetics and Pharmacometrics Division, Servier, Suresnes, France., Fouliard S; Clinical Pharmacokinetics and Pharmacometrics Division, Servier, Suresnes, France., Burbridge M; Center for Therapeutic Innovation in Oncology, Servier, Suresnes, France., Chenel M; Clinical Pharmacokinetics and Pharmacometrics Division, Servier, Suresnes, France., Magni P; Laboratory of Bioinformatics, Mathematical Modelling and Synthetic Biology, Department of Electrical, Computer and Biomedical Engineering, Università degli Studi di Pavia, Pavia, Italy. |
| Source: | CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2021 Nov; Vol. 10 (11), pp. 1396-1411. Date of Electronic Publication: 2021 Oct 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2163-8306 |
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| DOI: | 10.1002/psp4.12710 |
