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p21 produces a bioactive secretome that places stressed cells under immunosurveillance.

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Title: p21 produces a bioactive secretome that places stressed cells under immunosurveillance.
Authors: Sturmlechner I; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Pediatrics, Molecular Genetics Section, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, Netherlands., Zhang C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA., Sine CC; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., van Deursen EJ; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Jeganathan KB; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Hamada N; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Grasic J; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Friedman D; Department of Immunology, Mayo Clinic, Rochester, MN, USA., Stutchman JT; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Can I; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA., Hamada M; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Lim DY; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Lee JH; Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA., Ordog T; Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Laberge RM; Unity Biotechnology, South San Francisco, CA 94080, USA., Shapiro V; Department of Immunology, Mayo Clinic, Rochester, MN, USA., Baker DJ; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA., Li H; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA., van Deursen JM; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.
Source: Science (New York, N.Y.) [Science] 2021 Oct 29; Vol. 374 (6567), pp. eabb3420. Date of Electronic Publication: 2021 Oct 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: p21 produces a bioactive secretome that places stressed cells under immunosurveillance.
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  Data: <searchLink fieldCode="AU" term="%22Sturmlechner+I%22">Sturmlechner I</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Pediatrics, Molecular Genetics Section, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Sine+CC%22">Sine CC</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22van+Deursen+EJ%22">van Deursen EJ</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Jeganathan+KB%22">Jeganathan KB</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Hamada+N%22">Hamada N</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Grasic+J%22">Grasic J</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Friedman+D%22">Friedman D</searchLink>; Department of Immunology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Stutchman+JT%22">Stutchman JT</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Can+I%22">Can I</searchLink>; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Hamada+M%22">Hamada M</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lim+DY%22">Lim DY</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Ordog+T%22">Ordog T</searchLink>; Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Laberge+RM%22">Laberge RM</searchLink>; Unity Biotechnology, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Shapiro+V%22">Shapiro V</searchLink>; Department of Immunology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Baker+DJ%22">Baker DJ</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22van+Deursen+JM%22">van Deursen JM</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.
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  Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2021 Oct 29; Vol. 374 (6567), pp. eabb3420. <i>Date of Electronic Publication: </i>2021 Oct 29.
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