Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199.
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| Title: | Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199. |
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| Authors: | Wang BT; IGM Biosciences Inc., Mountain View, California., Kothambawala T; IGM Biosciences Inc., Mountain View, California., Wang L; IGM Biosciences Inc., Mountain View, California., Matthew TJ; IGM Biosciences Inc., Mountain View, California., Calhoun SE; IGM Biosciences Inc., Mountain View, California., Saini AK; IGM Biosciences Inc., Mountain View, California., Kotturi MF; IGM Biosciences Inc., Mountain View, California., Hernandez G; IGM Biosciences Inc., Mountain View, California., Humke EW; IGM Biosciences Inc., Mountain View, California., Peterson MS; IGM Biosciences Inc., Mountain View, California., Sinclair AM; IGM Biosciences Inc., Mountain View, California., Keyt BA; IGM Biosciences Inc., Mountain View, California. bkeyt@igmbio.com. |
| Source: | Molecular cancer therapeutics [Mol Cancer Ther] 2021 Dec; Vol. 20 (12), pp. 2483-2494. Date of Electronic Publication: 2021 Oct 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1538-8514 |
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| DOI: | 10.1158/1535-7163.MCT-20-1132 |
