Paradoxical Potentiation of Acid-Sensing Ion Channel 3 (ASIC3) by Amiloride via Multiple Mechanisms and Sites Within the Channel.

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Title: Paradoxical Potentiation of Acid-Sensing Ion Channel 3 (ASIC3) by Amiloride via Multiple Mechanisms and Sites Within the Channel.
Authors: Matasic DS; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, United States., Holland N; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, IA, United States., Gautam M; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.; Iowa City VA Healthcare System, Iowa City, IA, United States., Gibbons DD; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.; Iowa City VA Healthcare System, Iowa City, IA, United States., Kusama N; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.; Iowa City VA Healthcare System, Iowa City, IA, United States., Harding AMS; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.; Iowa City VA Healthcare System, Iowa City, IA, United States., Shah VS; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, United States., Snyder PM; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, United States.; Iowa City VA Healthcare System, Iowa City, IA, United States., Benson CJ; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, IA, United States.; Iowa City VA Healthcare System, Iowa City, IA, United States.
Source: Frontiers in physiology [Front Physiol] 2021 Oct 15; Vol. 12, pp. 750696. Date of Electronic Publication: 2021 Oct 15 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101549006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-042X (Print) Linking ISSN: 1664042X NLM ISO Abbreviation: Front Physiol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-042X
DOI:10.3389/fphys.2021.750696