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Thermodynamic Understanding of an Aza-Michael Reaction Enables Five-Step Synthesis of the Potent Integrin Inhibitor MK-0429.

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Title: Thermodynamic Understanding of an Aza-Michael Reaction Enables Five-Step Synthesis of the Potent Integrin Inhibitor MK-0429.
Authors: Gupta A; Department of Small Molecule Drug Discovery, Bristol Myers Squibb Company, 100 Binney Street, Cambridge, Massachusetts 02142, United States., Condakes ML; Department of Small Molecule Drug Discovery, Bristol Myers Squibb Company, 100 Binney Street, Cambridge, Massachusetts 02142, United States.
Source: The Journal of organic chemistry [J Org Chem] 2021 Dec 03; Vol. 86 (23), pp. 17523-17527. Date of Electronic Publication: 2021 Nov 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Thermodynamic Understanding of an Aza-Michael Reaction Enables Five-Step Synthesis of the Potent Integrin Inhibitor MK-0429.
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  Data: <searchLink fieldCode="AU" term="%22Gupta+A%22">Gupta A</searchLink>; Department of Small Molecule Drug Discovery, Bristol Myers Squibb Company, 100 Binney Street, Cambridge, Massachusetts 02142, United States.<br /><searchLink fieldCode="AU" term="%22Condakes+ML%22">Condakes ML</searchLink>; Department of Small Molecule Drug Discovery, Bristol Myers Squibb Company, 100 Binney Street, Cambridge, Massachusetts 02142, United States.
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  Data: <searchLink fieldCode="JN" term="%222985193R%22">The Journal of organic chemistry</searchLink> [J Org Chem] 2021 Dec 03; Vol. 86 (23), pp. 17523-17527. <i>Date of Electronic Publication: </i>2021 Nov 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985193R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-6904 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223263%22">00223263 </searchLink><i>NLM ISO Abbreviation: </i>J Org Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.joc.1c02375
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      – Code: eng
        Text: English
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        StartPage: 17523
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      – TitleFull: Thermodynamic Understanding of an Aza-Michael Reaction Enables Five-Step Synthesis of the Potent Integrin Inhibitor MK-0429.
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            NameFull: Gupta A
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              Text: 2021 Dec 03
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              Y: 2021
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