Thermodynamic Understanding of an Aza-Michael Reaction Enables Five-Step Synthesis of the Potent Integrin Inhibitor MK-0429.
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| Title: | Thermodynamic Understanding of an Aza-Michael Reaction Enables Five-Step Synthesis of the Potent Integrin Inhibitor MK-0429. |
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| Authors: | Gupta A; Department of Small Molecule Drug Discovery, Bristol Myers Squibb Company, 100 Binney Street, Cambridge, Massachusetts 02142, United States., Condakes ML; Department of Small Molecule Drug Discovery, Bristol Myers Squibb Company, 100 Binney Street, Cambridge, Massachusetts 02142, United States. |
| Source: | The Journal of organic chemistry [J Org Chem] 2021 Dec 03; Vol. 86 (23), pp. 17523-17527. Date of Electronic Publication: 2021 Nov 01. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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