Lactate supports a metabolic-epigenetic link in macrophage polarization.

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Title: Lactate supports a metabolic-epigenetic link in macrophage polarization.
Authors: Noe JT; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY 40202, USA.; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA., Rendon BE; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA., Geller AE; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.; Department of Microbiology and Immunology, University of Louisville, Louisville, KY 40202, USA., Conroy LR; Department of Neuroscience, University of Kentucky, Lexington, KY 40536, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA., Morrissey SM; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.; Department of Microbiology and Immunology, University of Louisville, Louisville, KY 40202, USA., Young LEA; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY 40536, USA., Bruntz RC; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY 40536, USA., Kim EJ; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA., Wise-Mitchell A; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA., Barbosa de Souza Rizzo M; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA., Relich ER; Department of Neuroscience, University of Kentucky, Lexington, KY 40536, USA., Baby BV; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA., Johnson LA; Department of Physiology, University of Kentucky, Lexington, KY 40536, USA.; Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40356, USA., Affronti HC; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., McMasters KM; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.; Division of Immunotherapy, Department of Surgery, University of Louisville, Louisville, KY 40202, USA., Clem BF; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY 40202, USA.; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA., Gentry MS; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY 40536, USA., Yan J; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.; Department of Microbiology and Immunology, University of Louisville, Louisville, KY 40202, USA.; Division of Immunotherapy, Department of Surgery, University of Louisville, Louisville, KY 40202, USA., Wellen KE; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Sun RC; Department of Neuroscience, University of Kentucky, Lexington, KY 40536, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA.; Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40356, USA., Mitchell RA; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY 40202, USA.; J.G. Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.; Department of Microbiology and Immunology, University of Louisville, Louisville, KY 40202, USA.; Division of Immunotherapy, Department of Surgery, University of Louisville, Louisville, KY 40202, USA.
Source: Science advances [Sci Adv] 2021 Nov 12; Vol. 7 (46), pp. eabi8602. Date of Electronic Publication: 2021 Nov 12.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2375-2548
DOI:10.1126/sciadv.abi8602