Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics.

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Title: Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics.
Authors: He Z; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA; Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address: zihuai@stanford.edu., Le Guen Y; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA; Institut du Cerveau - Paris Brain Institute - ICM, Paris 75013, France., Liu L; Department of Statistics, University of Pittsburgh, Pittsburgh, PA 15260, USA., Lee J; Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA 94305, USA., Ma S; Department of Biostatistics, Columbia University, New York, NY 10032, USA., Yang AC; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Liu X; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Rutledge J; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Losada PM; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Song B; Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA 94305, USA., Belloy ME; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Butler RR 3rd; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Longo FM; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Tang H; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Mormino EC; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Wyss-Coray T; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Greicius MD; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Ionita-Laza I; Department of Biostatistics, Columbia University, New York, NY 10032, USA.
Source: American journal of human genetics [Am J Hum Genet] 2021 Dec 02; Vol. 108 (12), pp. 2336-2353. Date of Electronic Publication: 2021 Nov 11.
Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1537-6605
DOI:10.1016/j.ajhg.2021.10.009