Co-targeting BET bromodomain BRD4 and RAC1 suppresses growth, stemness and tumorigenesis by disrupting the c-MYC-G9a-FTH1axis and downregulating HDAC1 in molecular subtypes of breast cancer.
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| Title: | Co-targeting BET bromodomain BRD4 and RAC1 suppresses growth, stemness and tumorigenesis by disrupting the c-MYC-G9a-FTH1axis and downregulating HDAC1 in molecular subtypes of breast cancer. |
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| Authors: | Ali A; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates., Shafarin J; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates., Unnikannan H; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates., Al-Jabi N; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Jabal RA; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Bajbouj K; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Muhammad JS; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Hamad M; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; Department of Medical Laboratory Sciences, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates. |
| Source: | International journal of biological sciences [Int J Biol Sci] 2021 Oct 25; Vol. 17 (15), pp. 4474-4492. Date of Electronic Publication: 2021 Oct 25 (Print Publication: 2021). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34803511 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Co-targeting BET bromodomain BRD4 and RAC1 suppresses growth, stemness and tumorigenesis by disrupting the c-MYC-G9a-FTH1axis and downregulating HDAC1 in molecular subtypes of breast cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ali+A%22">Ali A</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Shafarin+J%22">Shafarin J</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Unnikannan+H%22">Unnikannan H</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Al-Jabi+N%22">Al-Jabi N</searchLink>; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Jabal+RA%22">Jabal RA</searchLink>; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Bajbouj+K%22">Bajbouj K</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Muhammad+JS%22">Muhammad JS</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Hamad+M%22">Hamad M</searchLink>; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; Department of Medical Laboratory Sciences, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101235568%22">International journal of biological sciences</searchLink> [Int J Biol Sci] 2021 Oct 25; Vol. 17 (15), pp. 4474-4492. <i>Date of Electronic Publication: </i>2021 Oct 25 (<i>Print Publication: </i>2021). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International%22">Ivyspring International </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101235568 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1449-2288 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214492288%22">14492288 </searchLink><i>NLM ISO Abbreviation: </i>Int J Biol Sci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34803511 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7150/ijbs.62236 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 4474 Titles: – TitleFull: Co-targeting BET bromodomain BRD4 and RAC1 suppresses growth, stemness and tumorigenesis by disrupting the c-MYC-G9a-FTH1axis and downregulating HDAC1 in molecular subtypes of breast cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ali A – PersonEntity: Name: NameFull: Shafarin J – PersonEntity: Name: NameFull: Unnikannan H – PersonEntity: Name: NameFull: Al-Jabi N – PersonEntity: Name: NameFull: Jabal RA – PersonEntity: Name: NameFull: Bajbouj K – PersonEntity: Name: NameFull: Muhammad JS – PersonEntity: Name: NameFull: Hamad M IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 10 Text: 2021 Oct 25 Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1449-2288 Numbering: – Type: volume Value: 17 – Type: issue Value: 15 Titles: – TitleFull: International journal of biological sciences Type: main |
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