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Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer.

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Title: Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer.
Authors: Joshi S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Gomes ED; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Wang T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Corben A; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Taldone T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Gandu S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Xu C; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Sharma S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Buddaseth S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Yan P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Chan LYL; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Gokce A; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Rajasekhar VK; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Shrestha L; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Panchal P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Almodovar J; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Digwal CS; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Rodina A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Merugu S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Pillarsetty N; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Miclea V; Faculty of Automation and Computer Science, Technical University of Cluj-Napoca, Cluj-Napoca, CJ, 400114, Romania., Peter RI; Faculty of Automation and Computer Science, Technical University of Cluj-Napoca, Cluj-Napoca, CJ, 400114, Romania., Wang W; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Ginsberg SD; Center for Dementia Research, Nathan Kline Institute, Orangeburg, NY, 10962, USA.; Departments of Psychiatry, Neuroscience & Physiology, and the NYU Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, 10016, USA., Tang L; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Mattar M; Antitumour Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., de Stanchina E; Antitumour Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Yu KH; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Lowery M; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Grbovic-Huezo O; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., O'Reilly EM; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Janjigian Y; Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, 10065, USA., Healey JH; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Jarnagin WR; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Allen PJ; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA., Sander C; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, 02115, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA., Erdjument-Bromage H; Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, 10016, USA.; Kimmel Center for Biology and Medicine at the Skirball Institute, NYU School of Medicine, New York, NY, 10016, USA., Neubert TA; Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, 10016, USA.; Kimmel Center for Biology and Medicine at the Skirball Institute, NYU School of Medicine, New York, NY, 10016, USA., Leach SD; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Dartmouth Geisel School of Medicine and Norris Cotton Cancer Center, Lebanon, NH, 03766, USA., Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. chiosisg@mskcc.org.; Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, 10065, USA. chiosisg@mskcc.org.
Source: Communications biology [Commun Biol] 2021 Nov 25; Vol. 4 (1), pp. 1333. Date of Electronic Publication: 2021 Nov 25.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
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