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Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.

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Title: Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
Authors: Kummer MP; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany., Ising C; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Kummer C; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany., Sarlus H; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Griep A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Vieira-Saecker A; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany., Schwartz S; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany., Halle A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Brückner M; Caesar Research Center, Bonn, Germany., Händler K; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and University of Bonn, Bonn, Germany., Schultze JL; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and University of Bonn, Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Beyer M; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and University of Bonn, Bonn, Germany.; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Latz E; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute of Innate Immunity, University of Bonn, Bonn, Germany.; Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA, USA., Heneka MT; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA, USA.
Source: The EMBO journal [EMBO J] 2021 Dec 15; Vol. 40 (24), pp. e108662. Date of Electronic Publication: 2021 Nov 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
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  Data: <searchLink fieldCode="AU" term="%22Kummer+MP%22">Kummer MP</searchLink>; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Ising+C%22">Ising C</searchLink>; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Kummer+C%22">Kummer C</searchLink>; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Sarlus+H%22">Sarlus H</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Griep+A%22">Griep A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Vieira-Saecker+A%22">Vieira-Saecker A</searchLink>; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Schwartz+S%22">Schwartz S</searchLink>; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Halle+A%22">Halle A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Brückner+M%22">Brückner M</searchLink>; Caesar Research Center, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Händler+K%22">Händler K</searchLink>; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Schultze+JL%22">Schultze JL</searchLink>; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and University of Bonn, Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Beyer+M%22">Beyer M</searchLink>; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and University of Bonn, Bonn, Germany.; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Latz+E%22">Latz E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute of Innate Immunity, University of Bonn, Bonn, Germany.; Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Heneka+MT%22">Heneka MT</searchLink>; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Faculty, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%228208664%22">The EMBO journal</searchLink> [EMBO J] 2021 Dec 15; Vol. 40 (24), pp. e108662. <i>Date of Electronic Publication: </i>2021 Nov 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8208664 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2075 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202614189%22">02614189 </searchLink><i>NLM ISO Abbreviation: </i>EMBO J <i>Subsets: </i>MEDLINE
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