Deletion of the Stress Response Gene DDR48 from Histoplasma capsulatum Increases Sensitivity to Oxidative Stress, Increases Susceptibility to Antifungals, and Decreases Fitness in Macrophages.

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Title: Deletion of the Stress Response Gene DDR48 from Histoplasma capsulatum Increases Sensitivity to Oxidative Stress, Increases Susceptibility to Antifungals, and Decreases Fitness in Macrophages.
Authors: Blancett LT; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA.; Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Runge KA; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA.; ThruPore Technologies, Inc., New Castle, DE 19720, USA., Reyes GM; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA., Kennedy LA; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA.; Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS 39216, USA., Jackson SC; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA., Scheuermann SE; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA.; Mississippi INBRE Research Scholars Program, Mississippi INBRE, The University of Southern Mississippi, Hattiesburg, MS 39406, USA.; High Containment Research Performance Core, Tulane National Primate Research Center, Covington, LA 70433, USA., Harmon MB; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA.; Mississippi INBRE Research Scholars Program, Mississippi INBRE, The University of Southern Mississippi, Hattiesburg, MS 39406, USA., Williams JC; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA.; Mississippi INBRE Research Scholars Program, Mississippi INBRE, The University of Southern Mississippi, Hattiesburg, MS 39406, USA., Shearer G Jr; Center for Molecular and Cellular Biology, The University of Southern Mississippi, Hattiesburg, MS 39406, USA.
Source: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2021 Nov 18; Vol. 7 (11). Date of Electronic Publication: 2021 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101671827 Publication Model: Electronic Cited Medium: Internet ISSN: 2309-608X (Electronic) Linking ISSN: 2309608X NLM ISO Abbreviation: J Fungi (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2309-608X
DOI:10.3390/jof7110981