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An activity-based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti-fibrotic therapeutic strategies.

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Title: An activity-based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti-fibrotic therapeutic strategies.
Authors: Findlay A; Pharmaxis, Frenchs Forest, New South Wales, Australia., Turner C; Pharmaxis, Frenchs Forest, New South Wales, Australia., Schilter H; Pharmaxis, Frenchs Forest, New South Wales, Australia., Deodhar M; Pharmaxis, Frenchs Forest, New South Wales, Australia., Zhou W; Pharmaxis, Frenchs Forest, New South Wales, Australia., Perryman L; Pharmaxis, Frenchs Forest, New South Wales, Australia., Foot J; Pharmaxis, Frenchs Forest, New South Wales, Australia., Zahoor A; Pharmaxis, Frenchs Forest, New South Wales, Australia., Yao Y; Pharmaxis, Frenchs Forest, New South Wales, Australia., Hamilton R; Pharmaxis, Frenchs Forest, New South Wales, Australia., Brock M; Quanterix, Billerica, Massachusetts, USA., Raso C; Quanterix, Billerica, Massachusetts, USA., Stolp J; Pharmaxis, Frenchs Forest, New South Wales, Australia., Galati M; Pharmaxis, Frenchs Forest, New South Wales, Australia., Hamprecht D; Pharmaxis, Frenchs Forest, New South Wales, Australia., Charlton B; Pharmaxis, Frenchs Forest, New South Wales, Australia., Jarolimek W; Pharmaxis, Frenchs Forest, New South Wales, Australia.
Source: Clinical and translational medicine [Clin Transl Med] 2021 Nov; Vol. 11 (11), pp. e572.
Publication Type: Letter
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326 (Electronic) Linking ISSN: 20011326 NLM ISO Abbreviation: Clin Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Findlay+A%22">Findlay A</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Turner+C%22">Turner C</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Schilter+H%22">Schilter H</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Deodhar+M%22">Deodhar M</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Zhou+W%22">Zhou W</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Perryman+L%22">Perryman L</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Foot+J%22">Foot J</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Zahoor+A%22">Zahoor A</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Yao+Y%22">Yao Y</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Hamilton+R%22">Hamilton R</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Brock+M%22">Brock M</searchLink>; Quanterix, Billerica, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Raso+C%22">Raso C</searchLink>; Quanterix, Billerica, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Stolp+J%22">Stolp J</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Galati+M%22">Galati M</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Hamprecht+D%22">Hamprecht D</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Charlton+B%22">Charlton B</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Jarolimek+W%22">Jarolimek W</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101597971%22">Clinical and translational medicine</searchLink> [Clin Transl Med] 2021 Nov; Vol. 11 (11), pp. e572.
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              Text: 2021 Nov
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