What makes a good prediction? Feature importance and beginning to open the black box of machine learning in genetics.
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| Title: | What makes a good prediction? Feature importance and beginning to open the black box of machine learning in genetics. |
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| Authors: | Musolf AM; Statistical Genetics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive Suite 1200, Baltimore, MD, 21224, USA., Holzinger ER; Target Sciences, Informatics and Predictive Sciences, Bristol Myers Squibb, Cambridge, MA, USA., Malley JD; Statistical Genetics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive Suite 1200, Baltimore, MD, 21224, USA., Bailey-Wilson JE; Statistical Genetics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive Suite 1200, Baltimore, MD, 21224, USA. jebw@mail.nih.gov. |
| Source: | Human genetics [Hum Genet] 2022 Sep; Vol. 141 (9), pp. 1515-1528. Date of Electronic Publication: 2021 Dec 04. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7613873 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1203 (Electronic) Linking ISSN: 03406717 NLM ISO Abbreviation: Hum Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-1203 |
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| DOI: | 10.1007/s00439-021-02402-z |
