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Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome.

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Title: Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome.
Authors: Roostaei T; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Klein HU; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Ma Y; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Felsky D; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada., Kivisäkk P; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Connor SM; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Kroshilina A; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Yung C; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Kaskow BJ; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Shao X; Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, CA, USA., Rhead B; Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, CA, USA., Ordovás JM; Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA., Absher DM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA., Arnett DK; College of Public Health, University of Kentucky, Lexington, KY, USA., Liu J; Advanced Science Research Center at the Graduate Center, Neuroscience Initiative, City University of New York, New York, NY, USA., Patsopoulos N; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Barcellos LF; Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, CA, USA., Weiner HL; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., De Jager PL; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA. pld2115@cumc.columbia.edu.
Source: Nature communications [Nat Commun] 2021 Dec 06; Vol. 12 (1), pp. 7078. Date of Electronic Publication: 2021 Dec 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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