Structure-guided design of multi-epitopes vaccine against variants of concern (VOCs) of SARS-CoV-2 and validation through In silico cloning and immune simulations.

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Title: Structure-guided design of multi-epitopes vaccine against variants of concern (VOCs) of SARS-CoV-2 and validation through In silico cloning and immune simulations.
Authors: Humayun F; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China. Electronic address: fahadhumayun@outlook.com., Cai Y; Shenzhen College of International Education 3, Antuoshan 6 Road, Futian, Shenzhen, China. Electronic address: s19099.cai@stu.scie.com.cn., Khan A; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China. Electronic address: abbaskhan@sjtu.edu.cn., Farhan SA; Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan. Electronic address: jcsccfana@yahoo.com., Khan F; National Institute of Health, Islamabad, Pakistan. Electronic address: fatimanasrullahkhan@gmail.com., Rana UI; Department of Radiology, General Hospital, Lahore, Pakistan. Electronic address: usman.ishrat@hotmail.com., Qamar AB; Department of Biosciences and Bioinformatics, COMSATS University, Islamabad, Pakistan. Electronic address: hussain.anum94@gmail.com., Fawad N; Poultry Research Institute, Rawalpindi, Pakistan. Electronic address: nasimfawad58@gmail.com., Shamas S; Department of Zoology, University of Gujrat, Gujrat, Pakistan. Electronic address: shaziashams@yahoo.com., Dongqing-Wei; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China; Peng Cheng National Laboratory, Vanke Cloud City Phase I Building 8, Xili Street, Nashan District, Shenzhen, Guangdong, 518055, PR China. Electronic address: dqwei@sjtu.edu.cn.
Source: Computers in biology and medicine [Comput Biol Med] 2022 Jan; Vol. 140, pp. 105122. Date of Electronic Publication: 2021 Dec 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1250250 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0534 (Electronic) Linking ISSN: 00104825 NLM ISO Abbreviation: Comput Biol Med Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0534
DOI:10.1016/j.compbiomed.2021.105122