Structure-guided design of multi-epitopes vaccine against variants of concern (VOCs) of SARS-CoV-2 and validation through In silico cloning and immune simulations.

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Title: Structure-guided design of multi-epitopes vaccine against variants of concern (VOCs) of SARS-CoV-2 and validation through In silico cloning and immune simulations.
Authors: Humayun F; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China. Electronic address: fahadhumayun@outlook.com., Cai Y; Shenzhen College of International Education 3, Antuoshan 6 Road, Futian, Shenzhen, China. Electronic address: s19099.cai@stu.scie.com.cn., Khan A; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China. Electronic address: abbaskhan@sjtu.edu.cn., Farhan SA; Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan. Electronic address: jcsccfana@yahoo.com., Khan F; National Institute of Health, Islamabad, Pakistan. Electronic address: fatimanasrullahkhan@gmail.com., Rana UI; Department of Radiology, General Hospital, Lahore, Pakistan. Electronic address: usman.ishrat@hotmail.com., Qamar AB; Department of Biosciences and Bioinformatics, COMSATS University, Islamabad, Pakistan. Electronic address: hussain.anum94@gmail.com., Fawad N; Poultry Research Institute, Rawalpindi, Pakistan. Electronic address: nasimfawad58@gmail.com., Shamas S; Department of Zoology, University of Gujrat, Gujrat, Pakistan. Electronic address: shaziashams@yahoo.com., Dongqing-Wei; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China; Peng Cheng National Laboratory, Vanke Cloud City Phase I Building 8, Xili Street, Nashan District, Shenzhen, Guangdong, 518055, PR China. Electronic address: dqwei@sjtu.edu.cn.
Source: Computers in biology and medicine [Comput Biol Med] 2022 Jan; Vol. 140, pp. 105122. Date of Electronic Publication: 2021 Dec 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1250250 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0534 (Electronic) Linking ISSN: 00104825 NLM ISO Abbreviation: Comput Biol Med Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Structure-guided design of multi-epitopes vaccine against variants of concern (VOCs) of SARS-CoV-2 and validation through In silico cloning and immune simulations.
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  Data: <searchLink fieldCode="AU" term="%22Humayun+F%22">Humayun F</searchLink>; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China. Electronic address: fahadhumayun@outlook.com.<br /><searchLink fieldCode="AU" term="%22Cai+Y%22">Cai Y</searchLink>; Shenzhen College of International Education 3, Antuoshan 6 Road, Futian, Shenzhen, China. Electronic address: s19099.cai@stu.scie.com.cn.<br /><searchLink fieldCode="AU" term="%22Khan+A%22">Khan A</searchLink>; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China. Electronic address: abbaskhan@sjtu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Farhan+SA%22">Farhan SA</searchLink>; Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan. Electronic address: jcsccfana@yahoo.com.<br /><searchLink fieldCode="AU" term="%22Khan+F%22">Khan F</searchLink>; National Institute of Health, Islamabad, Pakistan. Electronic address: fatimanasrullahkhan@gmail.com.<br /><searchLink fieldCode="AU" term="%22Rana+UI%22">Rana UI</searchLink>; Department of Radiology, General Hospital, Lahore, Pakistan. Electronic address: usman.ishrat@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Qamar+AB%22">Qamar AB</searchLink>; Department of Biosciences and Bioinformatics, COMSATS University, Islamabad, Pakistan. Electronic address: hussain.anum94@gmail.com.<br /><searchLink fieldCode="AU" term="%22Fawad+N%22">Fawad N</searchLink>; Poultry Research Institute, Rawalpindi, Pakistan. Electronic address: nasimfawad58@gmail.com.<br /><searchLink fieldCode="AU" term="%22Shamas+S%22">Shamas S</searchLink>; Department of Zoology, University of Gujrat, Gujrat, Pakistan. Electronic address: shaziashams@yahoo.com.<br /><searchLink fieldCode="AU" term="%22Dongqing-Wei%22">Dongqing-Wei</searchLink>; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200030, PR China; Peng Cheng National Laboratory, Vanke Cloud City Phase I Building 8, Xili Street, Nashan District, Shenzhen, Guangdong, 518055, PR China. Electronic address: dqwei@sjtu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%221250250%22">Computers in biology and medicine</searchLink> [Comput Biol Med] 2022 Jan; Vol. 140, pp. 105122. <i>Date of Electronic Publication: </i>2021 Dec 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1250250 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0534 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200104825%22">00104825 </searchLink><i>NLM ISO Abbreviation: </i>Comput Biol Med <i>Subsets: </i>MEDLINE; PubMed not MEDLINE
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        Value: 10.1016/j.compbiomed.2021.105122
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        Text: English
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              Text: 2022 Jan
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