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Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase.

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Title: Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase.
Authors: Bheemanaboina RRY; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States., de Souza ML; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, 225 Warren Street, Newark, New Jersey 07103, United States., Gonzalez ML; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States., Mahmood SU; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States., Eck T; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States., Kreiss T; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States., Aylor SO; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States., Roth A; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States., Lee P; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States., Pybus BS; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States., Colussi DJ; Moulder Center for Drug Discovery Research, Temple University, Philadelphia, Pennsylvania 19140, United States., Childers WE; Moulder Center for Drug Discovery Research, Temple University, Philadelphia, Pennsylvania 19140, United States., Gordon J; Moulder Center for Drug Discovery Research, Temple University, Philadelphia, Pennsylvania 19140, United States., Siekierka JJ; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States., Bhanot P; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, 225 Warren Street, Newark, New Jersey 07103, United States., Rotella DP; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Nov 15; Vol. 12 (12), pp. 1962-1967. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
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  Data: Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase.
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  Data: <searchLink fieldCode="AU" term="%22Bheemanaboina+RRY%22">Bheemanaboina RRY</searchLink>; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States.<br /><searchLink fieldCode="AU" term="%22de+Souza+ML%22">de Souza ML</searchLink>; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, 225 Warren Street, Newark, New Jersey 07103, United States.<br /><searchLink fieldCode="AU" term="%22Gonzalez+ML%22">Gonzalez ML</searchLink>; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States.<br /><searchLink fieldCode="AU" term="%22Mahmood+SU%22">Mahmood SU</searchLink>; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States.<br /><searchLink fieldCode="AU" term="%22Eck+T%22">Eck T</searchLink>; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States.<br /><searchLink fieldCode="AU" term="%22Kreiss+T%22">Kreiss T</searchLink>; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States.<br /><searchLink fieldCode="AU" term="%22Aylor+SO%22">Aylor SO</searchLink>; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Roth+A%22">Roth A</searchLink>; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Lee+P%22">Lee P</searchLink>; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Pybus+BS%22">Pybus BS</searchLink>; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Colussi+DJ%22">Colussi DJ</searchLink>; Moulder Center for Drug Discovery Research, Temple University, Philadelphia, Pennsylvania 19140, United States.<br /><searchLink fieldCode="AU" term="%22Childers+WE%22">Childers WE</searchLink>; Moulder Center for Drug Discovery Research, Temple University, Philadelphia, Pennsylvania 19140, United States.<br /><searchLink fieldCode="AU" term="%22Gordon+J%22">Gordon J</searchLink>; Moulder Center for Drug Discovery Research, Temple University, Philadelphia, Pennsylvania 19140, United States.<br /><searchLink fieldCode="AU" term="%22Siekierka+JJ%22">Siekierka JJ</searchLink>; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States.<br /><searchLink fieldCode="AU" term="%22Bhanot+P%22">Bhanot P</searchLink>; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, 225 Warren Street, Newark, New Jersey 07103, United States.<br /><searchLink fieldCode="AU" term="%22Rotella+DP%22">Rotella DP</searchLink>; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, New Jersey 07043, United States.
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        Value: 10.1021/acsmedchemlett.1c00540
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        Text: English
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        StartPage: 1962
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              Text: 2021 Nov 15
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