Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel.

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Title: Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel.
Authors: Le Clec'h W; Texas Biomedical Research Institute, San Antonio, TX 78227, USA., Chevalier FD; Texas Biomedical Research Institute, San Antonio, TX 78227, USA., Mattos ACA; University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA., Strickland A; Texas Biomedical Research Institute, San Antonio, TX 78227, USA., Diaz R; Texas Biomedical Research Institute, San Antonio, TX 78227, USA., McDew-White M; Texas Biomedical Research Institute, San Antonio, TX 78227, USA., Rohr CM; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Kinung'hi S; National Institute for Medical Research, Mwanza, United Republic of Tanzania., Allan F; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial College, London, UK.; Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, UK., Webster BL; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial College, London, UK.; Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, UK., Webster JP; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial College, London, UK.; Centre for Emerging, Endemic and Exotic Diseases (CEEED), Royal Veterinary College, University of London, London, UK., Emery AM; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial College, London, UK.; Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, UK., Rollinson D; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial College, London, UK.; Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, UK., Djirmay AG; Réseau International Schistosomiases Environnemental Aménagement et Lutte (RISEAL), Niamey, Niger.; World Health Organization, Geneva, Switzerland., Al Mashikhi KM; Directorate General of Health Services, Dhofar Governorate, Salalah, Sultanate of Oman., Al Yafae S; Directorate General of Health Services, Dhofar Governorate, Salalah, Sultanate of Oman., Idris MA; Sultan Qaboos University, Muscat, Sultanate of Oman., Moné H; Host-Pathogen-Environment Interactions Laboratory, University of Perpignan, Perpignan, France., Mouahid G; Host-Pathogen-Environment Interactions Laboratory, University of Perpignan, Perpignan, France., LoVerde P; University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA., Marchant JS; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Anderson TJC; Texas Biomedical Research Institute, San Antonio, TX 78227, USA.
Source: Science translational medicine [Sci Transl Med] 2021 Dec 22; Vol. 13 (625), pp. eabj9114. Date of Electronic Publication: 2021 Dec 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.abj9114