Intracellularly Released Cholesterol from Polymer-Based Delivery Systems Alters Cellular Responses to Pneumolysin and Promotes Cell Survival.

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Title: Intracellularly Released Cholesterol from Polymer-Based Delivery Systems Alters Cellular Responses to Pneumolysin and Promotes Cell Survival.
Authors: Kammann T; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Nanophysiology Group, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Hoff J; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Nanophysiology Group, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Yildirim I; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany., Shkodra B; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany., Müller T; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07740 Jena, Germany.; Center for Molecular Biomedicine (CMB), Jena University Hospital, Hans-Knöll-Str. 2, 07745 Jena, Germany., Weber C; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany., Gräler MH; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07740 Jena, Germany.; Center for Molecular Biomedicine (CMB), Jena University Hospital, Hans-Knöll-Str. 2, 07745 Jena, Germany., Maus UA; Division of Experimental Pneumology, Medical School Hannover (MHH), Feodor-Lynen-Str. 21, 30625 Hannover, Germany.; German Center for Lung Research, Partner Site BREATH (Biomedical Research in Endstage and Obstructive Lung Disease Hannover), Carl-Neuberg-Str. 1, 30625 Hannover, Germany., Paton JC; Research Centre for Infectious Diseases, Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, SA 5005, Australia., Singer M; Centre for Intensive Care Medicine, Department of Medicine, Wolfson Institute for Biomedical Research, The Cruciform Building, University College London Hospital, Gower Street, London WC1E 6BT, UK., Traeger A; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany., Schubert US; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany., Bauer M; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Nanophysiology Group, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany., Press AT; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Nanophysiology Group, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Medical Faculty, Friedrich Schiller University Jena, Bachstr. 18, 07743 Jena, Germany.
Source: Metabolites [Metabolites] 2021 Nov 30; Vol. 11 (12). Date of Electronic Publication: 2021 Nov 30.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101578790 Publication Model: Electronic Cited Medium: Print ISSN: 2218-1989 (Print) Linking ISSN: 22181989 NLM ISO Abbreviation: Metabolites Subsets: PubMed not MEDLINE
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  Data: Intracellularly Released Cholesterol from Polymer-Based Delivery Systems Alters Cellular Responses to Pneumolysin and Promotes Cell Survival.
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  Data: <searchLink fieldCode="AU" term="%22Kammann+T%22">Kammann T</searchLink>; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Nanophysiology Group, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Hoff+J%22">Hoff J</searchLink>; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Nanophysiology Group, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Yildirim+I%22">Yildirim I</searchLink>; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Shkodra+B%22">Shkodra B</searchLink>; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+T%22">Müller T</searchLink>; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07740 Jena, Germany.; Center for Molecular Biomedicine (CMB), Jena University Hospital, Hans-Knöll-Str. 2, 07745 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+C%22">Weber C</searchLink>; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Gräler+MH%22">Gräler MH</searchLink>; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07740 Jena, Germany.; Center for Molecular Biomedicine (CMB), Jena University Hospital, Hans-Knöll-Str. 2, 07745 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Maus+UA%22">Maus UA</searchLink>; Division of Experimental Pneumology, Medical School Hannover (MHH), Feodor-Lynen-Str. 21, 30625 Hannover, Germany.; German Center for Lung Research, Partner Site BREATH (Biomedical Research in Endstage and Obstructive Lung Disease Hannover), Carl-Neuberg-Str. 1, 30625 Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Paton+JC%22">Paton JC</searchLink>; Research Centre for Infectious Diseases, Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, SA 5005, Australia.<br /><searchLink fieldCode="AU" term="%22Singer+M%22">Singer M</searchLink>; Centre for Intensive Care Medicine, Department of Medicine, Wolfson Institute for Biomedical Research, The Cruciform Building, University College London Hospital, Gower Street, London WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Traeger+A%22">Traeger A</searchLink>; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Schubert+US%22">Schubert US</searchLink>; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Bauer+M%22">Bauer M</searchLink>; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Nanophysiology Group, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Press+AT%22">Press AT</searchLink>; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Nanophysiology Group, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.; Medical Faculty, Friedrich Schiller University Jena, Bachstr. 18, 07743 Jena, Germany.
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