Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in chronic constriction injury (CCI) rats.

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Title: Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in chronic constriction injury (CCI) rats.
Authors: Li J; Laboratories of Neuroimmunology, Department of Symptom Research, The University of Texas, Houston, Texas, USA., Stratton HJ; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, Arizona, USA., Lorca SA; Laboratories of Neuroimmunology, Department of Symptom Research, The University of Texas, Houston, Texas, USA., Grace PM; Laboratories of Neuroimmunology, Department of Symptom Research, The University of Texas, Houston, Texas, USA., Khanna R; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, Arizona, USA.; Comprehensive Pain and Addiction Center, The University of Arizona, Tucson, Arizona, USA.
Source: Channels (Austin, Tex.) [Channels (Austin)] 2022 Dec; Vol. 16 (1), pp. 1-8.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101321614 Publication Model: Print Cited Medium: Internet ISSN: 1933-6969 (Electronic) Linking ISSN: 19336950 NLM ISO Abbreviation: Channels (Austin) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1933-6969
DOI:10.1080/19336950.2021.2023383