Functional impact and targetability of PI3KCA, GNAS, and PTEN mutations in a spindle cell rhabdomyosarcoma with MYOD1 L122R mutation.

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Title: Functional impact and targetability of PI3KCA, GNAS, and PTEN mutations in a spindle cell rhabdomyosarcoma with MYOD1 L122R mutation.
Authors: Choo F; Division of Pediatric Hematology/Oncology, Department of Pediatrics, Oregon Health and Science University (OHSU), Portland, Oregon 97239, USA., Odintsov I; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA., Nusser K; Division of Pediatric Hematology/Oncology, Department of Pediatrics, Oregon Health and Science University (OHSU), Portland, Oregon 97239, USA., Nicholson KS; Division of Pediatric Hematology/Oncology, Department of Pediatrics, Oregon Health and Science University (OHSU), Portland, Oregon 97239, USA., Davis L; Knight Cancer Institute, Division of Hematology/Oncology, OHSU, Portland, Oregon 97239, USA., Corless CL; Knight Cancer Institute and Department of Pathology, OHSU, Portland, Oregon 97239, USA., Stork L; Division of Pediatric Hematology/Oncology, Department of Pediatrics, Oregon Health and Science University (OHSU), Portland, Oregon 97239, USA., Somwar R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA., Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA., Davis JL; Knight Cancer Institute and Department of Pathology, OHSU, Portland, Oregon 97239, USA., Davare MA; Division of Pediatric Hematology/Oncology, Department of Pediatrics, Oregon Health and Science University (OHSU), Portland, Oregon 97239, USA.
Source: Cold Spring Harbor molecular case studies [Cold Spring Harb Mol Case Stud] 2022 Jan 10; Vol. 8 (1). Date of Electronic Publication: 2022 Jan 10 (Print Publication: 2022).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 101660017 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2873 (Electronic) Linking ISSN: 23732873 NLM ISO Abbreviation: Cold Spring Harb Mol Case Stud Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2373-2873
DOI:10.1101/mcs.a006140