Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain.
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| Title: | Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain. |
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| Authors: | Braden K; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, MO 63104, USA., Stratton HJ; Department of Pharmacology, College of Medicine, the University of Arizona, Tucson, AZ 85724, USA., Salvemini D; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, MO 63104, USA., Khanna R; Department of Pharmacology, College of Medicine, the University of Arizona, Tucson, AZ 85724, USA.; Comprehensive Pain and Addiction Center, The University of Arizona, Tucson, AZ 85724, USA. |
| Source: | Neurobiology of pain (Cambridge, Mass.) [Neurobiol Pain] 2021 Dec 27; Vol. 11, pp. 100082. Date of Electronic Publication: 2021 Dec 27 (Print Publication: 2022). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 101705141 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-073X (Electronic) Linking ISSN: 2452073X NLM ISO Abbreviation: Neurobiol Pain Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2452-073X |
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| DOI: | 10.1016/j.ynpai.2021.100082 |
