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Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain.

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Title: Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain.
Authors: Braden K; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, MO 63104, USA., Stratton HJ; Department of Pharmacology, College of Medicine, the University of Arizona, Tucson, AZ 85724, USA., Salvemini D; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, MO 63104, USA., Khanna R; Department of Pharmacology, College of Medicine, the University of Arizona, Tucson, AZ 85724, USA.; Comprehensive Pain and Addiction Center, The University of Arizona, Tucson, AZ 85724, USA.
Source: Neurobiology of pain (Cambridge, Mass.) [Neurobiol Pain] 2021 Dec 27; Vol. 11, pp. 100082. Date of Electronic Publication: 2021 Dec 27 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 101705141 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-073X (Electronic) Linking ISSN: 2452073X NLM ISO Abbreviation: Neurobiol Pain Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain.
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  Data: <searchLink fieldCode="AU" term="%22Braden+K%22">Braden K</searchLink>; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.<br /><searchLink fieldCode="AU" term="%22Stratton+HJ%22">Stratton HJ</searchLink>; Department of Pharmacology, College of Medicine, the University of Arizona, Tucson, AZ 85724, USA.<br /><searchLink fieldCode="AU" term="%22Salvemini+D%22">Salvemini D</searchLink>; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.<br /><searchLink fieldCode="AU" term="%22Khanna+R%22">Khanna R</searchLink>; Department of Pharmacology, College of Medicine, the University of Arizona, Tucson, AZ 85724, USA.; Comprehensive Pain and Addiction Center, The University of Arizona, Tucson, AZ 85724, USA.
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  Data: <searchLink fieldCode="JN" term="%22101705141%22">Neurobiology of pain (Cambridge, Mass.)</searchLink> [Neurobiol Pain] 2021 Dec 27; Vol. 11, pp. 100082. <i>Date of Electronic Publication: </i>2021 Dec 27 (<i>Print Publication: </i>2022).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+Inc%22">Elsevier, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101705141 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2452-073X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222452073X%22">2452073X </searchLink><i>NLM ISO Abbreviation: </i>Neurobiol Pain <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.ynpai.2021.100082
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      – TitleFull: Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain.
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              Text: 2021 Dec 27
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