Modeling uniquely human gene regulatory function via targeted humanization of the mouse genome.

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Title: Modeling uniquely human gene regulatory function via targeted humanization of the mouse genome.
Authors: Dutrow EV; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Emera D; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Center for Reproductive Longevity and Equality, Buck Institute for Research on Aging, Novato, CA, 94945, USA., Yim K; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA., Uebbing S; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA., Kocher AA; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA., Krenzer M; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Neuroscience Research Training Program, Department of Psychiatry, Yale School of Medicine, New Haven, CT, 06510, USA., Nottoli T; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, 06510, USA.; Yale Genome Editing Center, Yale School of Medicine, New Haven, CT, 06510, USA., Burkhardt DB; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Cellarity, Cambridge, MA, 02139, USA., Krishnaswamy S; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Computer Science, Yale University, New Haven, CT, 06520, USA., Louvi A; Department of Neurosurgery, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA., Noonan JP; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA. james.noonan@yale.edu.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA. james.noonan@yale.edu.; Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, 06520, USA. james.noonan@yale.edu.
Source: Nature communications [Nat Commun] 2022 Jan 13; Vol. 13 (1), pp. 304. Date of Electronic Publication: 2022 Jan 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Dutrow+EV%22">Dutrow EV</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Emera+D%22">Emera D</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Center for Reproductive Longevity and Equality, Buck Institute for Research on Aging, Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Yim+K%22">Yim K</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Uebbing+S%22">Uebbing S</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Kocher+AA%22">Kocher AA</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Krenzer+M%22">Krenzer M</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Neuroscience Research Training Program, Department of Psychiatry, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Nottoli+T%22">Nottoli T</searchLink>; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, 06510, USA.; Yale Genome Editing Center, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Burkhardt+DB%22">Burkhardt DB</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Cellarity, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Krishnaswamy+S%22">Krishnaswamy S</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Computer Science, Yale University, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Louvi+A%22">Louvi A</searchLink>; Department of Neurosurgery, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Noonan+JP%22">Noonan JP</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA. james.noonan@yale.edu.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA. james.noonan@yale.edu.; Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, 06520, USA. james.noonan@yale.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Jan 13; Vol. 13 (1), pp. 304. <i>Date of Electronic Publication: </i>2022 Jan 13.
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