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Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.

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Title: Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.
Authors: Kandasamy P; Wave Life Sciences, Cambridge, MA 02138, USA., Liu Y; Wave Life Sciences, Cambridge, MA 02138, USA., Aduda V; Wave Life Sciences, Cambridge, MA 02138, USA., Akare S; Wave Life Sciences, Cambridge, MA 02138, USA., Alam R; Wave Life Sciences, Cambridge, MA 02138, USA., Andreucci A; Wave Life Sciences, Cambridge, MA 02138, USA., Boulay D; Wave Life Sciences, Cambridge, MA 02138, USA., Bowman K; Wave Life Sciences, Cambridge, MA 02138, USA., Byrne M; Wave Life Sciences, Cambridge, MA 02138, USA., Cannon M; Wave Life Sciences, Cambridge, MA 02138, USA., Chivatakarn O; Wave Life Sciences, Cambridge, MA 02138, USA., Shelke JD; Wave Life Sciences, Cambridge, MA 02138, USA., Iwamoto N; Wave Life Sciences, Cambridge, MA 02138, USA., Kawamoto T; Wave Life Sciences, Cambridge, MA 02138, USA., Kumarasamy J; Wave Life Sciences, Cambridge, MA 02138, USA., Lamore S; Wave Life Sciences, Cambridge, MA 02138, USA., Lemaitre M; Wave Life Sciences, Cambridge, MA 02138, USA., Lin X; Wave Life Sciences, Cambridge, MA 02138, USA., Longo K; Wave Life Sciences, Cambridge, MA 02138, USA., Looby R; Wave Life Sciences, Cambridge, MA 02138, USA., Marappan S; Wave Life Sciences, Cambridge, MA 02138, USA., Metterville J; Wave Life Sciences, Cambridge, MA 02138, USA., Mohapatra S; Wave Life Sciences, Cambridge, MA 02138, USA., Newman B; Wave Life Sciences, Cambridge, MA 02138, USA., Paik IH; Wave Life Sciences, Cambridge, MA 02138, USA., Patil S; Wave Life Sciences, Cambridge, MA 02138, USA., Purcell-Estabrook E; Wave Life Sciences, Cambridge, MA 02138, USA., Shimizu M; Wave Life Sciences, Cambridge, MA 02138, USA., Shum P; Wave Life Sciences, Cambridge, MA 02138, USA., Standley S; Wave Life Sciences, Cambridge, MA 02138, USA., Taborn K; Wave Life Sciences, Cambridge, MA 02138, USA., Tripathi S; Wave Life Sciences, Cambridge, MA 02138, USA., Yang H; Wave Life Sciences, Cambridge, MA 02138, USA., Yin Y; Wave Life Sciences, Cambridge, MA 02138, USA., Zhao X; Wave Life Sciences, Cambridge, MA 02138, USA., Dale E; Wave Life Sciences, Cambridge, MA 02138, USA., Vargeese C; Wave Life Sciences, Cambridge, MA 02138, USA.
Source: Nucleic acids research [Nucleic Acids Res] 2022 Jun 10; Vol. 50 (10), pp. 5401-5423.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1362-4962
DOI:10.1093/nar/gkac037