Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.

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Bibliographic Details
Title: Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.
Authors: Cherney EC; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Zhang L; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Lo J; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Huynh T; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Wei D; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Ahuja V; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Quesnelle C; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Schieven GL; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Futran A; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Locke GA; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Lin Z; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Monereau L; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Chaudhry C; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Blum J; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Li S; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Fereshteh M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Li-Wang B; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Gangwar S; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Pan C; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Chong C; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Zhu X; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Posy SL; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Sack JS; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Zhang P; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Ruzanov M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Harner M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Akhtar F; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Schroeder GM; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Vite G; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Fink B; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
Source: Journal of medicinal chemistry [J Med Chem] 2022 Feb 24; Vol. 65 (4), pp. 3518-3538. Date of Electronic Publication: 2022 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4804
DOI:10.1021/acs.jmedchem.1c01986