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A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo.

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Title: A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo.
Authors: Humpton TJ; The Francis Crick Institute, London NW1 1AT, UK.; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Hock AK; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Kiourtis C; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., De Donatis M; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Fercoq F; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Nixon C; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Bryson S; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Strathdee D; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Carlin LM; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Bird TG; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Blyth K; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Vousden KH; The Francis Crick Institute, London NW1 1AT, UK.
Source: Science signaling [Sci Signal] 2022 Feb 08; Vol. 15 (720), pp. eabd9099. Date of Electronic Publication: 2022 Feb 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1937-9145
DOI:10.1126/scisignal.abd9099