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Safety and Pharmacokinetics of Monoclonal Antibodies VRC07-523LS and PGT121 Administered Subcutaneously for Human Immunodeficiency Virus Prevention.

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Title: Safety and Pharmacokinetics of Monoclonal Antibodies VRC07-523LS and PGT121 Administered Subcutaneously for Human Immunodeficiency Virus Prevention.
Authors: Mahomed S; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa., Garrett N; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; Department of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa., Capparelli EV; University of California, San Diego, California, USA., Osman F; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa., Harkoo I; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa., Yende-Zuma N; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa., Gengiah TN; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa., Archary D; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa., Samsunder N; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa., Baxter C; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa., Mkhize NN; National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa.; Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Modise T; National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa., Carlton K; Vaccine Research Centre, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., McDermott A; Vaccine Research Centre, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Moore PL; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa.; Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Karim QA; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; Department of Epidemiology, Columbia University, New York, New York, USA., Barouch DH; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Fast PE; International AIDS Vaccine Initiative, New York, New York, USA.; Pediatric Infectious Diseases, Stanford University School of Medicine, Palo Alto, California, USA., Mascola JR; Vaccine Research Centre, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Ledgerwood JE; Vaccine Research Centre, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Morris L; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa.; Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Abdool Karim SS; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; Department of Epidemiology, Columbia University, New York, New York, USA.
Source: The Journal of infectious diseases [J Infect Dis] 2022 Aug 26; Vol. 226 (3), pp. 510-520.
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety and Pharmacokinetics of Monoclonal Antibodies VRC07-523LS and PGT121 Administered Subcutaneously for Human Immunodeficiency Virus Prevention.
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  Data: <searchLink fieldCode="AU" term="%22Mahomed+S%22">Mahomed S</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Garrett+N%22">Garrett N</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; Department of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Capparelli+EV%22">Capparelli EV</searchLink>; University of California, San Diego, California, USA.<br /><searchLink fieldCode="AU" term="%22Osman+F%22">Osman F</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Harkoo+I%22">Harkoo I</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Yende-Zuma+N%22">Yende-Zuma N</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Gengiah+TN%22">Gengiah TN</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Archary+D%22">Archary D</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Samsunder+N%22">Samsunder N</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Baxter+C%22">Baxter C</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Mkhize+NN%22">Mkhize NN</searchLink>; National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa.; Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Modise+T%22">Modise T</searchLink>; National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Carlton+K%22">Carlton K</searchLink>; Vaccine Research Centre, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22McDermott+A%22">McDermott A</searchLink>; Vaccine Research Centre, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Moore+PL%22">Moore PL</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa.; Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Karim+QA%22">Karim QA</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; Department of Epidemiology, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Barouch+DH%22">Barouch DH</searchLink>; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Fast+PE%22">Fast PE</searchLink>; International AIDS Vaccine Initiative, New York, New York, USA.; Pediatric Infectious Diseases, Stanford University School of Medicine, Palo Alto, California, USA.<br /><searchLink fieldCode="AU" term="%22Mascola+JR%22">Mascola JR</searchLink>; Vaccine Research Centre, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Ledgerwood+JE%22">Ledgerwood JE</searchLink>; Vaccine Research Centre, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Morris+L%22">Morris L</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa.; Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Abdool+Karim+SS%22">Abdool Karim SS</searchLink>; CAPRISA, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; Department of Epidemiology, Columbia University, New York, New York, USA.
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  Data: <searchLink fieldCode="JN" term="%220413675%22">The Journal of infectious diseases</searchLink> [J Infect Dis] 2022 Aug 26; Vol. 226 (3), pp. 510-520.
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  Data: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0413675 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1537-6613 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221899%22">00221899 </searchLink><i>NLM ISO Abbreviation: </i>J Infect Dis <i>Subsets: </i>MEDLINE
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