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In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells.

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Title: In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells.
Authors: Huang B; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. bonniehuangnih@gmail.com.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA. bonniehuangnih@gmail.com., Phelan JD; National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Preite S; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Gomez-Rodriguez J; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; TCR2 Therapeutics, Cambridge, MA, 02142, USA., Johansen KH; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Shibata H; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Shaffer AL 3rd; National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Xu Q; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Jeffrey B; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Kirby M; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Anderson S; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Yang Y; National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Gossa S; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892, USA., McGavern DB; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892, USA., Staudt LM; National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Schwartzberg PL; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. pams@nih.gov.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA. pams@nih.gov.
Source: Nature communications [Nat Commun] 2022 Feb 10; Vol. 13 (1), pp. 805. Date of Electronic Publication: 2022 Feb 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells.
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  Data: <searchLink fieldCode="AU" term="%22Huang+B%22">Huang B</searchLink>; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. bonniehuangnih@gmail.com.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA. bonniehuangnih@gmail.com.<br /><searchLink fieldCode="AU" term="%22Phelan+JD%22">Phelan JD</searchLink>; National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Preite+S%22">Preite S</searchLink>; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Gomez-Rodriguez+J%22">Gomez-Rodriguez J</searchLink>; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; TCR2 Therapeutics, Cambridge, MA, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Johansen+KH%22">Johansen KH</searchLink>; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Shibata+H%22">Shibata H</searchLink>; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Shaffer+AL+3rd%22">Shaffer AL 3rd</searchLink>; National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Jeffrey+B%22">Jeffrey B</searchLink>; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Kirby+M%22">Kirby M</searchLink>; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+S%22">Anderson S</searchLink>; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Gossa+S%22">Gossa S</searchLink>; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22McGavern+DB%22">McGavern DB</searchLink>; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Staudt+LM%22">Staudt LM</searchLink>; National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Schwartzberg+PL%22">Schwartzberg PL</searchLink>; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. pams@nih.gov.; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA. pams@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Feb 10; Vol. 13 (1), pp. 805. <i>Date of Electronic Publication: </i>2022 Feb 10.
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