Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting.

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Title: Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting.
Authors: Jouandin P; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Marelja Z; Université de Paris, INSERM, IHU Imagine - Institut des maladies génétiques, Laboratory of Epithelial Biology and Disease, 75015 Paris, France.; Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany., Shih YH; Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany., Parkhitko AA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Dambowsky M; Université de Paris, INSERM, IHU Imagine - Institut des maladies génétiques, Laboratory of Epithelial Biology and Disease, 75015 Paris, France., Asara JM; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02175, USA., Nemazanyy I; Platform for Metabolic Analyses, Structure Fédérative de Recherche Necker, INSERM US24/CNRS UMS 3633, Paris 75015, France., Dibble CC; Department of Pathology and Cancer Center, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA., Simons M; Université de Paris, INSERM, IHU Imagine - Institut des maladies génétiques, Laboratory of Epithelial Biology and Disease, 75015 Paris, France.; Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany., Perrimon N; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.
Source: Science (New York, N.Y.) [Science] 2022 Feb 18; Vol. 375 (6582), pp. eabc4203. Date of Electronic Publication: 2022 Feb 18.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
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  Data: Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting.
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  Data: <searchLink fieldCode="AU" term="%22Jouandin+P%22">Jouandin P</searchLink>; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Marelja+Z%22">Marelja Z</searchLink>; Université de Paris, INSERM, IHU Imagine - Institut des maladies génétiques, Laboratory of Epithelial Biology and Disease, 75015 Paris, France.; Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Shih+YH%22">Shih YH</searchLink>; Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Parkhitko+AA%22">Parkhitko AA</searchLink>; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Dambowsky+M%22">Dambowsky M</searchLink>; Université de Paris, INSERM, IHU Imagine - Institut des maladies génétiques, Laboratory of Epithelial Biology and Disease, 75015 Paris, France.<br /><searchLink fieldCode="AU" term="%22Asara+JM%22">Asara JM</searchLink>; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02175, USA.<br /><searchLink fieldCode="AU" term="%22Nemazanyy+I%22">Nemazanyy I</searchLink>; Platform for Metabolic Analyses, Structure Fédérative de Recherche Necker, INSERM US24/CNRS UMS 3633, Paris 75015, France.<br /><searchLink fieldCode="AU" term="%22Dibble+CC%22">Dibble CC</searchLink>; Department of Pathology and Cancer Center, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Simons+M%22">Simons M</searchLink>; Université de Paris, INSERM, IHU Imagine - Institut des maladies génétiques, Laboratory of Epithelial Biology and Disease, 75015 Paris, France.; Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Perrimon+N%22">Perrimon N</searchLink>; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.
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  Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2022 Feb 18; Vol. 375 (6582), pp. eabc4203. <i>Date of Electronic Publication: </i>2022 Feb 18.
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              Text: 2022 Feb 18
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