A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M1 receptor agonist HTL0018318 in patients with mild-to-moderate Alzheimer's disease.
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| Title: | A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M |
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| Authors: | Nathan PJ; Heptares Therapeutics Ltd Cambridge UK.; Department of Psychiatry University of Cambridge Cambridge UK., Millais SB; Heptares Therapeutics Ltd Cambridge UK., Godwood A; Heptares Therapeutics Ltd Cambridge UK., Dewit O; Heptares Therapeutics Ltd Cambridge UK., Cross DM; Cross Pharma Consulting Limited Cambridge UK., Liptrot J; Heptares Therapeutics Ltd Cambridge UK., Ruparelia B; Heptares Therapeutics Ltd Cambridge UK., Jones SP; tranScrip Partners LLP Wokingham UK., Bakker G; Heptares Therapeutics Ltd Cambridge UK., Maruff PT; Cogstate Ltd New Haven Connecticut USA., Light GA; Department of Psychiatry University of San Diego San Diego California USA., Brown AJH; Heptares Therapeutics Ltd Cambridge UK., Weir MP; Heptares Therapeutics Ltd Cambridge UK., Congreve M; Heptares Therapeutics Ltd Cambridge UK., Tasker T; Heptares Therapeutics Ltd Cambridge UK. |
| Source: | Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2022 Feb 23; Vol. 8 (1), pp. e12273. Date of Electronic Publication: 2022 Feb 23 (Print Publication: 2022). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101650118 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-8737 (Electronic) Linking ISSN: 23528737 NLM ISO Abbreviation: Alzheimers Dement (N Y) Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2352-8737 |
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| DOI: | 10.1002/trc2.12273 |
