Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections.
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| Title: | Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections. |
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| Authors: | Chung H; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Merakou C; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Anaesthesia, Harvard Medical School, Boston, MA, USA., Schaefers MM; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Anaesthesia, Harvard Medical School, Boston, MA, USA., Flett KB; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.; Novant Health Eastover Pediatrics, Charlotte, NC, USA., Martini S; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA., Lu R; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA., Blumenthal JA; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Anaesthesia, Harvard Medical School, Boston, MA, USA., Webster SS; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA., Cross AR; Division of Pulmonary, Allergy & Immunology, Cystic Fibrosis and Sleep, Emory Children's Center for Cystic Fibrosis and Airway Disease Research, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Al Ahmar R; Department of Biomedical Science, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV, USA., Halpin E; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.; Winchester Hospital, Winchester, MA, USA., Anderson M; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.; Becton Dickinson, Franklin Lakes, NJ, USA., Moore NS; Harvard Medical School, Boston, MA, USA., Snesrud EC; Walter Reed Army Institute of Research, Silver Spring, MD, USA., Yu HD; Department of Biomedical Science, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV, USA.; Department of Pediatrics, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV, USA., Goldberg JB; Division of Pulmonary, Allergy & Immunology, Cystic Fibrosis and Sleep, Emory Children's Center for Cystic Fibrosis and Airway Disease Research, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., O'Toole GA; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA., McGann P; Walter Reed Army Institute of Research, Silver Spring, MD, USA., Stam JA; Walter Reed Army Institute of Research, Silver Spring, MD, USA., Hinkle M; Walter Reed Army Institute of Research, Silver Spring, MD, USA., McAdam AJ; Department of Laboratory Medicine, Boston Children's Hospital, Boston, MA, USA., Kishony R; Department of Systems Biology, Harvard Medical School, Boston, MA, USA. rkishony@technion.ac.il.; Faculty of Biology and Computer Science, Technion-Israel Institute of Technology, Haifa, Israel. rkishony@technion.ac.il., Priebe GP; Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA. gregory.priebe@childrens.harvard.edu.; Department of Anaesthesia, Harvard Medical School, Boston, MA, USA. gregory.priebe@childrens.harvard.edu. |
| Source: | Nature communications [Nat Commun] 2022 Mar 09; Vol. 13 (1), pp. 1231. Date of Electronic Publication: 2022 Mar 09. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-022-28188-w |