A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors.

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Title: A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors.
Authors: Awada G; Departments of Medical Oncology., Schwarze JK; Departments of Medical Oncology., Tijtgat J; Departments of Medical Oncology., Fasolino G; Ophthalmology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels., Kruse V; Department of Medical Oncology, Universitair Ziekenhuis Gent, Ghent.; Department of Medical Oncology, AZ Nikolaas, Sint-Niklaas (current affiliation).; Ghent University, Ghent (current affiliation).; University of Antwerp, Antwerp, Belgium (current affiliation)., Neyns B; Departments of Medical Oncology.
Source: Melanoma research [Melanoma Res] 2022 Jun 01; Vol. 32 (3), pp. 183-191. Date of Electronic Publication: 2022 Mar 29.
Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9109623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5636 (Electronic) Linking ISSN: 09608931 NLM ISO Abbreviation: Melanoma Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1473-5636
DOI:10.1097/CMR.0000000000000821