A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors.

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Title: A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors.
Authors: Awada G; Departments of Medical Oncology., Schwarze JK; Departments of Medical Oncology., Tijtgat J; Departments of Medical Oncology., Fasolino G; Ophthalmology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels., Kruse V; Department of Medical Oncology, Universitair Ziekenhuis Gent, Ghent.; Department of Medical Oncology, AZ Nikolaas, Sint-Niklaas (current affiliation).; Ghent University, Ghent (current affiliation).; University of Antwerp, Antwerp, Belgium (current affiliation)., Neyns B; Departments of Medical Oncology.
Source: Melanoma research [Melanoma Res] 2022 Jun 01; Vol. 32 (3), pp. 183-191. Date of Electronic Publication: 2022 Mar 29.
Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9109623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5636 (Electronic) Linking ISSN: 09608931 NLM ISO Abbreviation: Melanoma Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Awada+G%22">Awada G</searchLink>; Departments of Medical Oncology.<br /><searchLink fieldCode="AU" term="%22Schwarze+JK%22">Schwarze JK</searchLink>; Departments of Medical Oncology.<br /><searchLink fieldCode="AU" term="%22Tijtgat+J%22">Tijtgat J</searchLink>; Departments of Medical Oncology.<br /><searchLink fieldCode="AU" term="%22Fasolino+G%22">Fasolino G</searchLink>; Ophthalmology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels.<br /><searchLink fieldCode="AU" term="%22Kruse+V%22">Kruse V</searchLink>; Department of Medical Oncology, Universitair Ziekenhuis Gent, Ghent.; Department of Medical Oncology, AZ Nikolaas, Sint-Niklaas (current affiliation).; Ghent University, Ghent (current affiliation).; University of Antwerp, Antwerp, Belgium (current affiliation).<br /><searchLink fieldCode="AU" term="%22Neyns+B%22">Neyns B</searchLink>; Departments of Medical Oncology.
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  Data: <searchLink fieldCode="JN" term="%229109623%22">Melanoma research</searchLink> [Melanoma Res] 2022 Jun 01; Vol. 32 (3), pp. 183-191. <i>Date of Electronic Publication: </i>2022 Mar 29.
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  Data: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9109623 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1473-5636 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209608931%22">09608931 </searchLink><i>NLM ISO Abbreviation: </i>Melanoma Res <i>Subsets: </i>MEDLINE
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        Value: 10.1097/CMR.0000000000000821
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        Text: English
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      – TitleFull: A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors.
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              Text: 2022 Jun 01
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              Y: 2022
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