Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAFV600E /NRASQ61K malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model.
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| Title: | Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAFV600E /NRASQ61K malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model. |
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| Authors: | Jandova J; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Park SL; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Corenblum MJ; Department of Neurology, Evelyn F McKnight Brain Institute and BIO5 Institute, University of Arizona, Tucson, Arizona, USA., Madhavan L; Department of Neurology, Evelyn F McKnight Brain Institute and BIO5 Institute, University of Arizona, Tucson, Arizona, USA., Snell JA; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Rounds L; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Wondrak GT; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA. |
| Source: | Molecular carcinogenesis [Mol Carcinog] 2022 Jun; Vol. 61 (6), pp. 603-614. Date of Electronic Publication: 2022 Apr 13. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8811105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2744 (Electronic) Linking ISSN: 08991987 NLM ISO Abbreviation: Mol Carcinog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1098-2744 |
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| DOI: | 10.1002/mc.23407 |
