Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAFV600E /NRASQ61K malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model.
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| Title: | Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAFV600E /NRASQ61K malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model. |
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| Authors: | Jandova J; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Park SL; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Corenblum MJ; Department of Neurology, Evelyn F McKnight Brain Institute and BIO5 Institute, University of Arizona, Tucson, Arizona, USA., Madhavan L; Department of Neurology, Evelyn F McKnight Brain Institute and BIO5 Institute, University of Arizona, Tucson, Arizona, USA., Snell JA; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Rounds L; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Wondrak GT; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA. |
| Source: | Molecular carcinogenesis [Mol Carcinog] 2022 Jun; Vol. 61 (6), pp. 603-614. Date of Electronic Publication: 2022 Apr 13. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8811105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2744 (Electronic) Linking ISSN: 08991987 NLM ISO Abbreviation: Mol Carcinog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 35417045 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAF<superscript>V600E</superscript> /NRAS<superscript>Q61K</superscript> malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Jandova+J%22">Jandova J</searchLink>; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Park+SL%22">Park SL</searchLink>; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Corenblum+MJ%22">Corenblum MJ</searchLink>; Department of Neurology, Evelyn F McKnight Brain Institute and BIO5 Institute, University of Arizona, Tucson, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Madhavan+L%22">Madhavan L</searchLink>; Department of Neurology, Evelyn F McKnight Brain Institute and BIO5 Institute, University of Arizona, Tucson, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Snell+JA%22">Snell JA</searchLink>; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Rounds+L%22">Rounds L</searchLink>; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Wondrak+GT%22">Wondrak GT</searchLink>; Department of Pharmacology and Toxicology, RK Coit College of Pharmacy & The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228811105%22">Molecular carcinogenesis</searchLink> [Mol Carcinog] 2022 Jun; Vol. 61 (6), pp. 603-614. <i>Date of Electronic Publication: </i>2022 Apr 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Liss%22">Wiley-Liss </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8811105 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-2744 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208991987%22">08991987 </searchLink><i>NLM ISO Abbreviation: </i>Mol Carcinog <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=35417045 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mc.23407 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 603 Titles: – TitleFull: Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAFV600E /NRASQ61K malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jandova J – PersonEntity: Name: NameFull: Park SL – PersonEntity: Name: NameFull: Corenblum MJ – PersonEntity: Name: NameFull: Madhavan L – PersonEntity: Name: NameFull: Snell JA – PersonEntity: Name: NameFull: Rounds L – PersonEntity: Name: NameFull: Wondrak GT IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2022 Jun Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 1098-2744 Numbering: – Type: volume Value: 61 – Type: issue Value: 6 Titles: – TitleFull: Molecular carcinogenesis Type: main |
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