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Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors.

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Bibliographic Details
Title: Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors.
Authors: Snyder LA; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Damle R; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Patel S; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania., Bohrer J; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania., Fiorella A; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania., Driscoll J; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Hawkins R; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Stratton CF; Discovery Sciences, Janssen Research and Development, Spring House, Pennsylvania., Manning CD; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Tatikola K; Statistics and Decision Sciences, Janssen Research and Development, Raritan, New Jersey., Tryputsen V; Statistics and Decision Sciences, Janssen Research and Development, Spring House, Pennsylvania., Packman K; Oncology In Vivo Pharmacology, Janssen Research and Development, Spring House, Pennsylvania., Mamidi RNVS; Global Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Raritan, New Jersey.
Source: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Jul 05; Vol. 21 (7), pp. 1115-1124.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1538-8514
DOI:10.1158/1535-7163.MCT-21-0798