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Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors.

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Title: Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors.
Authors: Snyder LA; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Damle R; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Patel S; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania., Bohrer J; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania., Fiorella A; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania., Driscoll J; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Hawkins R; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Stratton CF; Discovery Sciences, Janssen Research and Development, Spring House, Pennsylvania., Manning CD; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania., Tatikola K; Statistics and Decision Sciences, Janssen Research and Development, Raritan, New Jersey., Tryputsen V; Statistics and Decision Sciences, Janssen Research and Development, Spring House, Pennsylvania., Packman K; Oncology In Vivo Pharmacology, Janssen Research and Development, Spring House, Pennsylvania., Mamidi RNVS; Global Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Raritan, New Jersey.
Source: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Jul 05; Vol. 21 (7), pp. 1115-1124.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Snyder+LA%22">Snyder LA</searchLink>; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Damle+R%22">Damle R</searchLink>; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Patel+S%22">Patel S</searchLink>; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Bohrer+J%22">Bohrer J</searchLink>; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Fiorella+A%22">Fiorella A</searchLink>; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Driscoll+J%22">Driscoll J</searchLink>; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Hawkins+R%22">Hawkins R</searchLink>; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Stratton+CF%22">Stratton CF</searchLink>; Discovery Sciences, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Manning+CD%22">Manning CD</searchLink>; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Tatikola+K%22">Tatikola K</searchLink>; Statistics and Decision Sciences, Janssen Research and Development, Raritan, New Jersey.<br /><searchLink fieldCode="AU" term="%22Tryputsen+V%22">Tryputsen V</searchLink>; Statistics and Decision Sciences, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Packman+K%22">Packman K</searchLink>; Oncology In Vivo Pharmacology, Janssen Research and Development, Spring House, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Mamidi+RNVS%22">Mamidi RNVS</searchLink>; Global Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Raritan, New Jersey.
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  Data: <searchLink fieldCode="JN" term="%22101132535%22">Molecular cancer therapeutics</searchLink> [Mol Cancer Ther] 2022 Jul 05; Vol. 21 (7), pp. 1115-1124.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%2C+Inc%22">American Association for Cancer Research, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101132535 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-8514 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215357163%22">15357163 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cancer Ther <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=35499386
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        Value: 10.1158/1535-7163.MCT-21-0798
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        Text: English
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              Text: 2022 Jul 05
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