Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells.
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| Title: | Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. |
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| Authors: | You Y; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Hersh SW; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA., Aslebagh R; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, Massachusetts, USA., Shaffer SA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, Massachusetts, USA., Ikezu S; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA., Mez J; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Logue MW; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, USA.; National Center for PTSD, Behavioral Sciences Division, VA Boston Healthcare System, Boston, Massachusetts, USA., Farrer LA; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA., Ikezu T; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA.; Center for Systems Neuroscience, Boston University, Boston, Massachusetts, USA. |
| Source: | Aging cell [Aging Cell] 2022 Jun; Vol. 21 (6), pp. e13617. Date of Electronic Publication: 2022 May 14. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1474-9726 |
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| DOI: | 10.1111/acel.13617 |
