Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells.

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Title: Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells.
Authors: You Y; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Hersh SW; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA., Aslebagh R; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, Massachusetts, USA., Shaffer SA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, Massachusetts, USA., Ikezu S; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA., Mez J; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Logue MW; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, USA.; National Center for PTSD, Behavioral Sciences Division, VA Boston Healthcare System, Boston, Massachusetts, USA., Farrer LA; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA., Ikezu T; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA.; Center for Systems Neuroscience, Boston University, Boston, Massachusetts, USA.
Source: Aging cell [Aging Cell] 2022 Jun; Vol. 21 (6), pp. e13617. Date of Electronic Publication: 2022 May 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
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  Data: Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells.
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  Data: <searchLink fieldCode="AU" term="%22You+Y%22">You Y</searchLink>; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Hersh+SW%22">Hersh SW</searchLink>; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Aslebagh+R%22">Aslebagh R</searchLink>; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Shaffer+SA%22">Shaffer SA</searchLink>; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ikezu+S%22">Ikezu S</searchLink>; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Mez+J%22">Mez J</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Lunetta+KL%22">Lunetta KL</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Logue+MW%22">Logue MW</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, USA.; National Center for PTSD, Behavioral Sciences Division, VA Boston Healthcare System, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Farrer+LA%22">Farrer LA</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ikezu+T%22">Ikezu T</searchLink>; Departments of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA.; Center for Systems Neuroscience, Boston University, Boston, Massachusetts, USA.
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  Data: <searchLink fieldCode="JN" term="%22101130839%22">Aging cell</searchLink> [Aging Cell] 2022 Jun; Vol. 21 (6), pp. e13617. <i>Date of Electronic Publication: </i>2022 May 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101130839 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-9726 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214749718%22">14749718 </searchLink><i>NLM ISO Abbreviation: </i>Aging Cell <i>Subsets: </i>MEDLINE
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              Text: 2022 Jun
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