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Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial.

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Title: Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial.
Authors: Toff WD; Department of Cardiovascular Sciences, University of Leicester, Leicester, England.; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, England., Hildick-Smith D; Sussex Cardiac Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, England., Kovac J; Department of Cardiovascular Sciences, University of Leicester, Leicester, England.; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, England., Mullen MJ; Institute of Cardiovascular Science, University College London, London, England., Wendler O; Department of Cardiothoracic Surgery, King's College Hospital NHS Foundation Trust, London, England., Mansouri A; Oxford Clinical Trials Research Unit, Nuffield Department of Orthopedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England., Rombach I; Oxford Clinical Trials Research Unit, Nuffield Department of Orthopedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England., Abrams KR; Centre for Health Economics, University of York, York, England.; Department of Statistics, University of Warwick, Coventry, England.; Department of Health Sciences, University of Leicester, Leicester, England., Conroy SP; Department of Health Sciences, University of Leicester, Leicester, England., Flather MD; Norwich Medical School, University of East Anglia, Norwich, England., Gray AM; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, England., MacCarthy P; Department of Cardiology, King's College Hospital NHS Foundation Trust, London, England., Monaghan MJ; Department of Cardiology, King's College Hospital NHS Foundation Trust, London, England., Prendergast B; Department of Cardiology, St Thomas' Hospital, London, England., Ray S; Department of Cardiology, Manchester University NHS Foundation Trust, Manchester, England., Young CP; Department of Cardiothoracic Surgery, St Thomas' Hospital, London, England., Crossman DC; School of Medicine, University of St Andrews, Fife, Scotland., Cleland JGF; Robertson Centre for Biostatistics and Glasgow Clinical Trials Unit, Institute of Health and Wellbeing, University of Glasgow, Glasgow, Scotland., de Belder MA; National Institute for Cardiovascular Outcomes Research, Barts Health NHS Trust, London, England., Ludman PF; Institute of Cardiovascular Sciences, Birmingham University, Birmingham, England., Jones S; Surgical Intervention Trials Unit, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, England., Densem CG; Department of Cardiology, Royal Papworth Hospital, Cambridge, England., Tsui S; Department of Cardiothoracic Surgery, Royal Papworth Hospital, Cambridge, England., Kuduvalli M; Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, England., Mills JD; Department of Cardiology, Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, England., Banning AP; Department of Cardiology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, England., Sayeed R; Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, England., Hasan R; Department of Cardiothoracic Surgery, Manchester University NHS Foundation Trust, Manchester, England., Fraser DGW; Department of Cardiovascular Medicine, University of Manchester, Manchester, England., Trivedi U; Sussex Cardiac Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, England., Davies SW; Cardiac Department, Royal Brompton Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, England., Duncan A; Cardiac Department, Royal Brompton Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, England., Curzen N; Wessex Cardiothoracic Centre, University Hospital Southampton, Southampton, England., Ohri SK; Wessex Cardiothoracic Centre, University Hospital Southampton, Southampton, England., Malkin CJ; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, England., Kaul P; Department of Cardiac Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, England., Muir DF; Department of Cardiology, James Cook University Hospital, South Tees Hospitals NHS Foundation Trust, Middlesbrough, England., Owens WA; Department of Cardiothoracic Surgery, James Cook University Hospital, South Tees Hospitals NHS Foundation Trust, Middlesbrough, England., Uren NG; Edinburgh Heart Centre, Royal Infirmary of Edinburgh, Edinburgh, Scotland., Pessotto R; Edinburgh Heart Centre, Royal Infirmary of Edinburgh, Edinburgh, Scotland., Kennon S; Barts Heart Centre, Barts Health NHS Trust, London, England., Awad WI; Barts Heart Centre, Barts Health NHS Trust, London, England., Khogali SS; Heart and Lung Centre, New Cross Hospital, Wolverhampton, England., Matuszewski M; Heart and Lung Centre, New Cross Hospital, Wolverhampton, England., Edwards RJ; Cardiothoracic Department, Newcastle upon Tyne Hospitals, Newcastle upon Tyne, England., Ramesh BC; Cardiothoracic Department, Newcastle upon Tyne Hospitals, Newcastle upon Tyne, England., Dalby M; Department of Cardiology, Harefield Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, England., Raja SG; Department of Cardiac Surgery, Harefield Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, England., Mariscalco G; Department of Cardiovascular Sciences, University of Leicester, Leicester, England.; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, England., Lloyd C; Department of Cardiothoracic Surgery, Derriford Hospital, Plymouth, England., Cox ID; Department of Cardiology, Derriford Hospital, Plymouth, England., Redwood SR; Cardiovascular Division, King's College London, British Heart Foundation Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, London, England., Gunning MG; Cardiology Department, Royal Stoke University Hospital, Stoke-on-Trent, England., Ridley PD; Department of Cardiothoracic Surgery, Royal Stoke University Hospital, Stoke-on-Trent, England.
Corporate Authors: UK TAVI Trial Investigators
Source: JAMA [JAMA] 2022 May 17; Vol. 327 (19), pp. 1875-1887.
Publication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial.
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