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A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.

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Bibliographic Details
Title: A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
Authors: Griffith DA; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Edmonds DJ; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Fortin JP; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Kalgutkar AS; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Kuzmiski JB; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Loria PM; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Saxena AR; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Bagley SW; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Buckeridge C; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Curto JM; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Derksen DR; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Dias JM; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Griffor MC; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Han S; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Jackson VM; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Landis MS; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Lettiere D; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Limberakis C; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Liu Y; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Mathiowetz AM; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Patel JC; Sosei Heptares, Cambridge CB21 6DG, U.K., Piotrowski DW; Pfizer Worldwide Research, Development, and Medical, Groton, Connecticut 06340, United States., Price DA; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Ruggeri RB; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States., Tess DA; Pfizer Worldwide Research, Development, and Medical, Cambridge, Massachusetts 02139, United States.
Source: Journal of medicinal chemistry [J Med Chem] 2022 Jun 23; Vol. 65 (12), pp. 8208-8226. Date of Electronic Publication: 2022 Jun 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4804
DOI:10.1021/acs.jmedchem.1c01856